PMID- 23938124
OWN - NLM
STAT- MEDLINE
DCOM- 20131223
LR  - 20131021
IS  - 1879-1891 (Electronic)
IS  - 0002-9394 (Linking)
VI  - 156
IP  - 5
DP  - 2013 Nov
TI  - Postoperative optical coherence tomographic appearance and relation to visual 
      acuity after vitrectomy for myopic foveoschisis.
PG  - 968-973.e1
LID - S0002-9394(13)00399-1 [pii]
LID - 10.1016/j.ajo.2013.06.011 [doi]
AB  - PURPOSE: To investigate the appearance of postoperative spectral-domain optical 
      coherence tomography (SD-OCT) and the relationship of the findings to visual 
      acuity in myopic foveoschisis. DESIGN: Retrospective observational case series. 
      METHODS: We studied 17 eyes (17 women; mean age, 66.4 years) with myopic 
      foveoschisis. SD-OCT was performed preoperatively and 1, 3, 6, and 12 months 
      after vitrectomy. The average central foveal thickness and choroidal thickness 
      and the integrity of the foveal photoreceptor inner segment/outer segment 
      junction as well as the external limiting membrane were correlated with the 
      postoperative best-corrected visual acuity (BCVA). RESULTS: The mean refractive 
      error was -11.9 diopters, axial length 29.7 mm, choroidal thickness 29.9 mum, and 
      logarithm of the maximum angle of resolution (logMAR) visual acuity 0.52 at 
      baseline. The mean preoperative central foveal thickness was 470.8 mum, which was 
      not associated with age, refractive error, symptom duration, or BCVA. The mean 
      postoperative retinal thicknesses at 1, 3, 6, and 12 months were 310.4, 251.8, 
      218.2, and 218.7 mum, respectively (P < 0.01 at all time points). The final BCVA 
      improved significantly (P < 0.001). The preoperative BCVA (P < 0.0001) difference 
      in central foveal thickness between 3 and 12 months postoperatively (P < 0.05), 
      the final integrity of the inner segment/outer segment junction (P < 0.05), and 
      the ELM (P < 0.05) were significantly associated with the final BCVA. The 
      preoperative choroidal thickness was negatively associated with axial length (P < 
      0.05) but not with postoperative central foveal thickness or BCVA. CONCLUSIONS: 
      The final BCVA in myopic foveoschisis is associated with the retinal thickness 
      changes postoperatively and recovery of the photoreceptor cells as seen in OCT 
      images.
CI  - Copyright (c) 2013 Elsevier Inc. All rights reserved.
FAU - Fujimoto, Satoko
AU  - Fujimoto S
AD  - Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, 
      Japan.
FAU - Ikuno, Yasushi
AU  - Ikuno Y
FAU - Nishida, Kohji
AU  - Nishida K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130812
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Axial Length, Eye
MH  - Endotamponade
MH  - Female
MH  - Follow-Up Studies
MH  - Fovea Centralis/pathology
MH  - Humans
MH  - Middle Aged
MH  - Myopia, Degenerative/pathology/*surgery
MH  - Postoperative Period
MH  - Retinal Photoreceptor Cell Inner Segment/pathology
MH  - Retinal Photoreceptor Cell Outer Segment/pathology
MH  - Retinoschisis/pathology/*surgery
MH  - Retrospective Studies
MH  - Time Factors
MH  - *Tomography, Optical Coherence
MH  - Visual Acuity/*physiology
MH  - *Vitrectomy
EDAT- 2013/08/14 06:00
MHDA- 2013/12/24 06:00
CRDT- 2013/08/14 06:00
PHST- 2012/12/26 00:00 [received]
PHST- 2013/06/07 00:00 [revised]
PHST- 2013/06/07 00:00 [accepted]
PHST- 2013/08/14 06:00 [entrez]
PHST- 2013/08/14 06:00 [pubmed]
PHST- 2013/12/24 06:00 [medline]
AID - S0002-9394(13)00399-1 [pii]
AID - 10.1016/j.ajo.2013.06.011 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2013 Nov;156(5):968-973.e1. doi: 10.1016/j.ajo.2013.06.011. Epub 
      2013 Aug 12.