PMID- 23942057
OWN - NLM
STAT- MEDLINE
DCOM- 20140707
LR  - 20211021
IS  - 1473-5571 (Electronic)
IS  - 0269-9370 (Linking)
VI  - 27
IP  - 17
DP  - 2013 Nov 13
TI  - HLA correlates in a cohort of slow progressors from China: effects on HIV-1 
      disease progression.
PG  - 2822-4
LID - 10.1097/QAD.0000000000000011 [doi]
AB  - We looked at our HIV + slow progressors cohort to determine if there were any 
      human leukocyte antigen (HLA) correlates for protection. No statistically 
      significant allelic differences were found between the HIV + and control cohorts 
      using regression analysis, though trends were noted. Data for Elite Controllers 
      showed an increased frequency of B*57. Likewise, no correlation was inferred with 
      the clinical data of the HIV + cohort. We hypothesize that the protective effect 
      of HLA alleles may have been lost over time.
FAU - Rai, Mohammad A
AU  - Rai MA
AD  - aNuffield Department of Medicine, John Radcliffe Hospital, Oxford, UK bBeijing 
      You'An Hospital, Capital Medical University, Beijing, China cCentre for 
      Statistics in Medicine, Oxford, UK dSchool of Public Health, Sun Yat-sen 
      University, Guangzhou, China eMRC Human Immunology Unit, Weatherall Institute of 
      Molecular Medicine, John Radcliffe Hospital, Oxford, UK fBeijing Ditan Hospital, 
      Capital Medical University, Beijing, China. *Marie-E. Blais and Ke Yi Xu 
      contributed equally to the writing of this article.
FAU - Zhang, Yonghong
AU  - Zhang Y
FAU - Yindom, Louis-M
AU  - Yindom LM
FAU - Holmes, Jane
AU  - Holmes J
FAU - Yu, Ly-Mee
AU  - Yu LM
FAU - Hao, Chun
AU  - Hao C
FAU - Rostron, Tim
AU  - Rostron T
FAU - Yan, Huiping
AU  - Yan H
FAU - Zhang, Yong Li
AU  - Zhang YL
FAU - Cai, Chao
AU  - Cai C
FAU - McMichael, Andrew J
AU  - McMichael AJ
FAU - Dong, Tao
AU  - Dong T
FAU - Rowland-Jones, Sarah L
AU  - Rowland-Jones SL
FAU - Blais, Marie-E
AU  - Blais ME
FAU - Xu, Ke Yi
AU  - Xu KY
LA  - eng
GR  - G0600520/MRC_/Medical Research Council/United Kingdom
GR  - G0801751/MRC_/Medical Research Council/United Kingdom
GR  - G1001046/MRC_/Medical Research Council/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - AIDS
JT  - AIDS (London, England)
JID - 8710219
RN  - 0 (La protein, human)
RN  - 0 (Phosphoproteins)
SB  - IM
MH  - China
MH  - Cohort Studies
MH  - Gene Frequency
MH  - HIV Infections/*genetics/*immunology
MH  - *HIV Long-Term Survivors
MH  - Humans
MH  - Phosphoproteins/*genetics
EDAT- 2013/08/15 06:00
MHDA- 2014/07/08 06:00
CRDT- 2013/08/15 06:00
PHST- 2013/08/15 06:00 [entrez]
PHST- 2013/08/15 06:00 [pubmed]
PHST- 2014/07/08 06:00 [medline]
AID - 10.1097/QAD.0000000000000011 [doi]
PST - ppublish
SO  - AIDS. 2013 Nov 13;27(17):2822-4. doi: 10.1097/QAD.0000000000000011.