PMID- 23947667
OWN - NLM
STAT- MEDLINE
DCOM- 20140304
LR  - 20130816
IS  - 1532-2378 (Electronic)
IS  - 1049-5398 (Linking)
VI  - 24
IP  - 4
DP  - 2013
TI  - Comparative messenger RNA expression of FSHbeta, LHbeta, FSHR, LHR, and ERbeta in high and 
      low prolific goat breeds.
PG  - 307-11
LID - 10.1080/10495398.2013.790824 [doi]
AB  - Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) have a central 
      role in follicle growth and maturation, but no clear differences between breeds 
      with different ovulation rates have been found. Therefore, this study 
      investigated mRNA expression of FSHbeta, LHbeta, FSH receptor (FSHR), LH receptor 
      (LHR), and estrogen receptor-beta (ERbeta) genes in prolific Lezhi black (LB) goats and 
      nonprolific Tibetan (TB) goats by real-time PCR. Follicles and pituitaries were 
      recovered from goats at 12-24 h after onset of estrus. Real-time PCR analysis 
      revealed that the expression levels of FSHbeta and LHbeta mRNA were significantly 
      higher (p < 0.01) in pituitary of LB than in TB does, but the expression levels 
      of FSHR and LHR mRNA in follicle of TB were greater (p < 0.05). Expression level 
      of follicular ER beta was not different between the two breeds. Data provide 
      evidence that the greater ovulation rate in the LB goat as compared to the TB 
      breed is associated with a greater gonadotropin expression during follicular 
      phase.
FAU - Zi, Xiang-Dong
AU  - Zi XD
AD  - a Sichuan Provincial Key-Laboratory of Protection and Utilization of Animal 
      Genetic Resources in Qinghai-Tibet Plateau, Southwest University for 
      Nationalities , Chengdu , P. R. China.
FAU - Huang, Lei
AU  - Huang L
FAU - Wang, Yong
AU  - Wang Y
FAU - Lu, Jian-Yuan
AU  - Lu JY
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Anim Biotechnol
JT  - Animal biotechnology
JID - 9011409
RN  - 0 (Estrogen Receptor beta)
RN  - 0 (Gonadotropins, Pituitary)
RN  - 0 (RNA, Messenger)
RN  - 0 (Receptors, Gonadotropin)
SB  - IM
MH  - Animals
MH  - Estrogen Receptor beta/*analysis/genetics/metabolism
MH  - Female
MH  - Gene Expression Profiling
MH  - Goats/genetics/*metabolism
MH  - Gonadotropins, Pituitary/*analysis/genetics/metabolism
MH  - Ovarian Follicle/chemistry/metabolism
MH  - Ovulation/genetics/physiology
MH  - Pituitary Gland/chemistry/metabolism
MH  - RNA, Messenger/*analysis/genetics/metabolism
MH  - Real-Time Polymerase Chain Reaction
MH  - Receptors, Gonadotropin/*analysis/genetics/metabolism
EDAT- 2013/08/21 06:00
MHDA- 2014/03/05 06:00
CRDT- 2013/08/17 06:00
PHST- 2013/08/17 06:00 [entrez]
PHST- 2013/08/21 06:00 [pubmed]
PHST- 2014/03/05 06:00 [medline]
AID - 10.1080/10495398.2013.790824 [doi]
PST - ppublish
SO  - Anim Biotechnol. 2013;24(4):307-11. doi: 10.1080/10495398.2013.790824.