PMID- 23949097
OWN - NLM
STAT- MEDLINE
DCOM- 20140527
LR  - 20151119
IS  - 1530-0315 (Electronic)
IS  - 0195-9131 (Linking)
VI  - 45
IP  - 9
DP  - 2013 Sep
TI  - Fructose-maltodextrin ratio governs exogenous and other CHO oxidation and 
      performance.
PG  - 1814-24
LID - 10.1249/MSS.0b013e31828e12d4 [doi]
AB  - INTRODUCTION: Fructose coingested with glucose in carbohydrate (CHO) drinks 
      increases exogenous-CHO oxidation, gut comfort, and physical performance. 
      PURPOSE: This study aimed to determine the effect of different 
      fructose-maltodextrin-glucose ratios on CHO oxidation and fluid absorption while 
      controlling for osmolality and caloricity. METHODS: In a crossover design, 12 
      male cyclists rode 2 h at 57% peak power then performed 10 sprints while 
      ingesting artificially sweetened water or three equiosmotic 11.25% CHO-salt 
      drinks at 200 mL.15 min, comprising weighed fructose and maltodextrin-glucose in 
      ratios of 0.5:1 (0.5 ratio), 0.8:1 (0.8 ratio), and 1.25:1 (1.25 ratio). Fluid 
      absorption was traced with D2O, whereas C-fructose and C-maltodextrin-glucose 
      permitted fructose and glucose oxidation rate evaluation. RESULTS: The mean 
      exogenous-fructose and exogenous-glucose oxidation rates were 0.27, 0.39, and 
      0.46 g.min and 0.65, 0.71, and 0.58 g.min in 0.5, 0.8, and 1.25 ratio drinks, 
      representing mean oxidation efficiencies of 54%, 59%, and 55% and 65%, 85%, and 
      86% for fructose and glucose, respectively. With the 0.8 ratio drink, total 
      exogenous-CHO oxidation rate was 18% (90% confidence interval, +/-5%) and 5.2% 
      (+/-4.6%) higher relative to 0.5 and 1.25 ratios, respectively, whereas respective 
      differences in total exogenous-CHO oxidation efficiency were 17% (+/-5%) and 5.3% 
      (+/-4.8%), associated with 8.6% and 7.8% (+/-4.2%) higher fructose oxidation 
      efficiency. The effects of CHO ratio on water absorption were inconclusive. Mean 
      sprint power with the 0.8 ratio drink was moderately higher than that with the 
      0.5 ratio (2.9%; 99% confidence interval, +/-2.8%) and 1.25 ratio (3.1%; +/-2.7%) 
      drinks, with total- and endogenous-CHO oxidation rate, abdominal cramps, and 
      drink sweetness qualifying as explanatory mechanisms. CONCLUSIONS: Enhanced 
      high-intensity endurance performance with a 0.8 ratio 
      fructose-maltodextrin-glucose drink is characterized by higher exogenous-CHO 
      oxidation efficiency and reduced endogenous-CHO oxidation. The gut-hepatic or 
      other physiological site responsible requires further research.
FAU - O'Brien, Wendy J
AU  - O'Brien WJ
AD  - School of Sport and Exercise, Massey University, Wellington, New Zealand.
FAU - Stannard, Stephen R
AU  - Stannard SR
FAU - Clarke, Jim A
AU  - Clarke JA
FAU - Rowlands, David Stephen
AU  - Rowlands DS
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Polysaccharides)
RN  - 30237-26-4 (Fructose)
RN  - 7CVR7L4A2D (maltodextrin)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - Athletic Performance/*physiology
MH  - Bicycling/*physiology
MH  - Cross-Over Studies
MH  - Double-Blind Method
MH  - Fructose/*administration & dosage/*metabolism/pharmacokinetics
MH  - Glucose/metabolism
MH  - Humans
MH  - Male
MH  - Muscle Fatigue
MH  - Myalgia
MH  - Nausea/etiology
MH  - Oxidation-Reduction
MH  - Physical Exertion
MH  - Polysaccharides/*administration & dosage/*metabolism/pharmacokinetics
MH  - Taste
EDAT- 2013/08/21 06:00
MHDA- 2014/05/28 06:00
CRDT- 2013/08/17 06:00
PHST- 2013/08/17 06:00 [entrez]
PHST- 2013/08/21 06:00 [pubmed]
PHST- 2014/05/28 06:00 [medline]
AID - 00005768-201309000-00021 [pii]
AID - 10.1249/MSS.0b013e31828e12d4 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2013 Sep;45(9):1814-24. doi: 10.1249/MSS.0b013e31828e12d4.