PMID- 23952990
OWN - NLM
STAT- MEDLINE
DCOM- 20130924
LR  - 20170310
IS  - 0022-9040 (Print)
IS  - 0022-9040 (Linking)
VI  - 53
IP  - 5
DP  - 2013
TI  - [An experience of the use of a curative method of cardiac shock wave therapy in 
      patients with ischemic heart disease].
PG  - 20-6
AB  - Aim of the study was to assess effects of cardiac shock wave therapy (CSWT) in 
      patients with coronary artery disease (CAD) with refractory stable angina 
      pectoris. Seventeen CAD patients with refractory II-IV class angina (3 women and 
      14 men, mean age 67.4+/-8.6 years) received the course of 9 procedures of CSWT. 
      All patients had I-III New York Heart Association (NYHA) class congestive heart 
      failure. Before and after CSWT medical examination with life quality assessment 
      by means of the Minnesota Living Questionnaire, echocardiography, veloergometry, 
      myocardial perfusion imaging with single-photon emission computed tomography 
      (SPECT) using 99M-Tc-methyl-iodine-benzyl-guanydin (MIBG) and Holter ECG 
      monitoring was performed. The dynamics of pro-angiogenic factors (VEGF, HGF, 
      FGF-) were also measured by ELISA, and of brain natriuretic peptide (Nt-proBNP) 
      by the electrochemoluminescence method. Most patients (80%) had significant life 
      quality (<0.01) and myocardial perfusion improvement. Episodes of angina pectoris 
      and nitrate intake were more than twice decreased. There was a significant 
      increase in exercise tolerance (p<0.01). Holter ECG monitoring showed decreasing 
      of an average heart rate (p<0.02); no worsening of previous cardiac arrhythmias 
      was observed. The significant (p<0.05) decreases in plasma Nt-proBNP and 
      increases in VEGF concentration were revealed after CSWT. CSWT procedures were 
      well tolerated. The results of our study confirm high effectiveness and safety of 
      CSWT in complex treatment of patients with CAD, resistant angina pectoris, 
      including patients after myocardial revascularization and with heart failure.
FAU - Gabrusenko, S A
AU  - Gabrusenko SA
FAU - Malakhov, V V
AU  - Malakhov VV
FAU - Shitov, V N
AU  - Shitov VN
FAU - Sankova, A N
AU  - Sankova AN
FAU - Sergienko, V B
AU  - Sergienko VB
FAU - Masenko, V P
AU  - Masenko VP
FAU - Kukharchuk, V V
AU  - Kukharchuk VV
LA  - rus
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
PL  - Russia (Federation)
TA  - Kardiologiia
JT  - Kardiologiia
JID - 0376351
SB  - IM
MH  - Aged
MH  - Coronary Angiography
MH  - Electrocardiography, Ambulatory
MH  - Female
MH  - Humans
MH  - Male
MH  - Myocardial Ischemia/diagnosis/*therapy
MH  - Short-Wave Therapy/*methods
MH  - Tomography, Emission-Computed, Single-Photon
MH  - Treatment Outcome
EDAT- 2013/08/21 06:00
MHDA- 2013/09/26 06:00
CRDT- 2013/08/20 06:00
PHST- 2013/08/20 06:00 [entrez]
PHST- 2013/08/21 06:00 [pubmed]
PHST- 2013/09/26 06:00 [medline]
PST - ppublish
SO  - Kardiologiia. 2013;53(5):20-6.