PMID- 23960654
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130820
LR  - 20220318
IS  - 1016-7315 (Print)
IS  - 2212-5043 (Electronic)
IS  - 1016-7315 (Linking)
VI  - 23
IP  - 4
DP  - 2011 Oct
TI  - Baseline characteristics, management practices, and in-hospital outcomes of 
      patients with acute coronary syndromes: Results of the Saudi project for 
      assessment of coronary events (SPACE) registry.
PG  - 233-9
LID - 10.1016/j.jsha.2011.05.004 [doi]
AB  - OBJECTIVES: The Saudi Project for Assessment of Coronary Events (SPACE) registry 
      is the first in Saudi Arabia to study the clinical features, management, and 
      in-hospital outcomes of acute coronary syndrome (ACS) patients. METHODS: We 
      conducted a prospective registry study in 17 hospitals in Saudi Arabia between 
      December 2005 and December 2007. ACS patients included those with ST-elevation 
      myocardial infarction (STEMI), non-ST elevation myocardial infarction and 
      unstable angina; both were reported collectively as NSTEACS (non-ST elevation 
      acute coronary syndrome). RESULTS: 5055 patients were enrolled with mean age +/- SD 
      of 58 +/- 12.9 years; 77.4% men, 82.4% Saudi nationals; 41.5% had STEMI, and 5.1% 
      arrived at the hospital by ambulance. History of diabetes mellitus was present in 
      58.1%, hypertension in 55.3%, hyperlipidemia in 41.1%, and 32.8% were current 
      smokers; all these were more common in NSTEACS patients, except for smoking (all 
      P < 0.0001). In-hospital medications were: aspirin (97.7%), clopidogrel (83.7%), 
      beta-blockers (81.6%), angiotensin converting enzyme inhibitors/angiotensin 
      receptor blockers (75.1%), and statins (93.3%). Median time from symptom onset to 
      hospital arrival for STEMI patients was 150 min (IQR: 223), 17.5% had primary 
      percutaneous coronary intervention (PCI), 69.1% had thrombolytic therapy, and 
      14.8% received it at less than 30 min of hospital arrival. In-hospital outcomes 
      included recurrent myocardial infarction (1.5%), recurrent ischemia (12.6%), 
      cardiogenic shock (4.3%), stroke (0.9%), major bleeding (1.3%). In-hospital 
      mortality was 3.0%. CONCLUSION: ACS patients in Saudi Arabia present at a younger 
      age, have much higher prevalence of diabetes mellitus, less access to ambulance 
      use, delayed treatment by thrombolytic therapy, and less primary PCI compared 
      with patients in the developed countries. This is the first national ACS registry 
      in our country and it demonstrated knowledge-care gaps that require further 
      improvements.
FAU - Alhabib, Khalid F
AU  - Alhabib KF
AD  - King Fahad Cardiac Center, King Khalid University Hospital, College of Medicine, 
      King Saud University, Saudi Arabia.
FAU - Hersi, Ahmad
AU  - Hersi A
FAU - Alfaleh, Hussam
AU  - Alfaleh H
FAU - Alnemer, Khalid
AU  - Alnemer K
FAU - Alsaif, Shukri
AU  - Alsaif S
FAU - Taraben, Amir
AU  - Taraben A
FAU - Kashour, Tarek
AU  - Kashour T
FAU - Bakheet, Anas
AU  - Bakheet A
FAU - Qarni, Ayed Al
AU  - Qarni AA
FAU - Soomro, Tariq
AU  - Soomro T
FAU - Malik, Asif
AU  - Malik A
FAU - Ahmed, Waqar H
AU  - Ahmed WH
FAU - Abuosa, Ahmed M
AU  - Abuosa AM
FAU - Butt, Modaser A
AU  - Butt MA
FAU - Almurayeh, Mushabab A
AU  - Almurayeh MA
FAU - Zaidi, Abdulaziz Al
AU  - Zaidi AA
FAU - Hussein, Gamal A
AU  - Hussein GA
FAU - Balghith, Mohammed A
AU  - Balghith MA
FAU - Abu-Ghazala, Tareg
AU  - Abu-Ghazala T
LA  - eng
PT  - Journal Article
DEP - 20110601
PL  - Saudi Arabia
TA  - J Saudi Heart Assoc
JT  - Journal of the Saudi Heart Association
JID - 9887261
PMC - PMC3727434
OTO - NOTNLM
OT  - Acute coronary syndromes
OT  - Acute myocardial infarction
OT  - Middle East
OT  - Registry
OT  - Saudi Arabia
OT  - Unstable angina
EDAT- 2011/10/01 00:00
MHDA- 2011/10/01 00:01
PMCR- 2011/06/01
CRDT- 2013/08/21 06:00
PHST- 2011/03/29 00:00 [received]
PHST- 2011/05/11 00:00 [revised]
PHST- 2011/05/23 00:00 [accepted]
PHST- 2013/08/21 06:00 [entrez]
PHST- 2011/10/01 00:00 [pubmed]
PHST- 2011/10/01 00:01 [medline]
PHST- 2011/06/01 00:00 [pmc-release]
AID - JSHA117 [pii]
AID - 10.1016/j.jsha.2011.05.004 [doi]
PST - ppublish
SO  - J Saudi Heart Assoc. 2011 Oct;23(4):233-9. doi: 10.1016/j.jsha.2011.05.004. Epub 
      2011 Jun 1.