PMID- 23962727
OWN - NLM
STAT- MEDLINE
DCOM- 20140806
LR  - 20131210
IS  - 1873-4030 (Electronic)
IS  - 1350-4533 (Linking)
VI  - 35
IP  - 12
DP  - 2013 Dec
TI  - Ventricular activity cancellation in electrograms during atrial fibrillation with 
      constraints on residuals' power.
PG  - 1770-7
LID - S1350-4533(13)00168-9 [pii]
LID - 10.1016/j.medengphy.2013.07.010 [doi]
AB  - During atrial fibrillation (AF), cancellation of ventricular activity from atrial 
      electrograms (AEG) is commonly performed by template matching and subtraction 
      (TMS): a running template, built in correspondence of QRSs, is subtracted from 
      the AEG to uncover atrial activity (AA). However, TMS can produce poor 
      cancellation, leaving high-power residues. In this study, we propose to modulate 
      the templates before subtraction, in order to make the residuals as similar as 
      possible to the nearby atrial activity, avoiding high-power ones. The 
      coefficients used to modulate the template are estimated by maximizing, via 
      Multi-swarm Particle Swarm Optimization, a fitness function. The modulated TMS 
      method (mTMS) was tested on synthetic and real AEGs. Cancellation performances 
      were assessed using: normalized mean squared error (NMSE, computed on simulated 
      data only), reduction of ventricular activity (VDR), and percentage of segments 
      (PP) whose power was outside the standard range of the atrial power. All testings 
      suggested that mTMS is an improvement over TMS alone, being, on simulated data, 
      NMSE and PP significantly decreased while VDR significantly increased. Similar 
      results were obtained on real electrograms (median values of CS1 recordings PP: 
      2.44 vs. 0.38 p < 0.001; VDR: 6.71 vs. 8.15 p < 0.001).
CI  - Copyright (c) 2013 IPEM. Published by Elsevier Ltd. All rights reserved.
FAU - Corino, Valentina D A
AU  - Corino VD
AD  - Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, 
      20133 Milan, Italy. Electronic address: valentina.corino@polimi.it.
FAU - Rivolta, Massimo W
AU  - Rivolta MW
FAU - Sassi, Roberto
AU  - Sassi R
FAU - Lombardi, Federico
AU  - Lombardi F
FAU - Mainardi, Luca T
AU  - Mainardi LT
LA  - eng
PT  - Journal Article
DEP - 20130818
PL  - England
TA  - Med Eng Phys
JT  - Medical engineering & physics
JID - 9422753
SB  - IM
MH  - Algorithms
MH  - Atrial Fibrillation/*physiopathology
MH  - Electrocardiography/*methods
MH  - Heart Atria/physiopathology
MH  - Heart Ventricles/*physiopathology
MH  - Humans
MH  - Models, Theoretical
MH  - *Signal Processing, Computer-Assisted
OTO - NOTNLM
OT  - Atrial electrograms
OT  - Atrial fibrillation
OT  - Multi-swarm Particle Swarm Optimization
OT  - Ventricular interference
EDAT- 2013/08/22 06:00
MHDA- 2014/08/07 06:00
CRDT- 2013/08/22 06:00
PHST- 2012/10/09 00:00 [received]
PHST- 2013/06/27 00:00 [revised]
PHST- 2013/07/27 00:00 [accepted]
PHST- 2013/08/22 06:00 [entrez]
PHST- 2013/08/22 06:00 [pubmed]
PHST- 2014/08/07 06:00 [medline]
AID - S1350-4533(13)00168-9 [pii]
AID - 10.1016/j.medengphy.2013.07.010 [doi]
PST - ppublish
SO  - Med Eng Phys. 2013 Dec;35(12):1770-7. doi: 10.1016/j.medengphy.2013.07.010. Epub 
      2013 Aug 18.