PMID- 23972540 OWN - NLM STAT- MEDLINE DCOM- 20150202 LR - 20131202 IS - 1528-3984 (Electronic) IS - 0197-4572 (Linking) VI - 34 IP - 6 DP - 2013 Nov-Dec TI - Slowing progression of early stages of AD with alternative therapies: a feasibility study. PG - 457-64 LID - S0197-4572(13)00252-8 [pii] LID - 10.1016/j.gerinurse.2013.07.003 [doi] AB - This pilot study identified the feasibility and efficacy of the effect of combining healing touch (HT) and body talk cortices (BTC) on the progression of Alzheimer's disease (AD). Both HT and BTC elicit the relaxation response and support cognitive function from two different perspectives. A two-group, repeated measures design was used. Subjects (n = 22), 65 or older with early stage (less than four) AD, residing in the community (n = 2) or in care agencies (n = 20), were assigned to either the HT-BTC group (n = 12) or the control group (n = 10) randomized by residence. The treatment group received, 6 months of weekly HT and performed the BTC technique daily. The usual medical regimen for all subjects was continued. The control group had no additional interventions. Both groups were assessed at baseline, 3 and 6 months. The groups did not differ significantly at baseline on cognitive reserve, age, gender, and ethnicity, nor on the outcome variables (cognitive function, mood, & depression). Adherence (76%) to the BTC protocol, the major feasibility problem, related to memory deficits. Significant interactions occurred regarding cognitive function and mood. Significant improvements in cognitive function (p = .008), mood (p = .001), and depression (p = .028) were observed in the treatment group which is not the usual course of AD. A decline in cognitive function occurred in the control group typical of AD's usual course. Although the number of subjects in this pilot study was small, and there were feasibility challenges with recruitment and adherence, important trends were noted suggesting areas for future study. CI - Published by Mosby, Inc. FAU - Lu, Der-Fa AU - Lu DF AD - The University of Iowa, College of Nursing, 50 Newton Road, Iowa City, IA 52242-1121, USA. Electronic address: der-fa-lu@uiowa.edu. FAU - Hart, Laura K AU - Hart LK FAU - Lutgendorf, Susan K AU - Lutgendorf SK FAU - Oh, Hyunkyoung AU - Oh H FAU - Schilling, Margo AU - Schilling M LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20130822 PL - United States TA - Geriatr Nurs JT - Geriatric nursing (New York, N.Y.) JID - 8309633 MH - Aged MH - Aged, 80 and over MH - Alzheimer Disease/*pathology/therapy MH - *Complementary Therapies MH - Disease Progression MH - Feasibility Studies MH - Female MH - Humans MH - Male OTO - NOTNLM OT - Alzheimer's disease OT - Biofield interventions OT - Body talk cortices OT - Healing touch EDAT- 2013/08/27 06:00 MHDA- 2015/02/03 06:00 CRDT- 2013/08/27 06:00 PHST- 2013/04/18 00:00 [received] PHST- 2013/07/08 00:00 [revised] PHST- 2013/07/14 00:00 [accepted] PHST- 2013/08/27 06:00 [entrez] PHST- 2013/08/27 06:00 [pubmed] PHST- 2015/02/03 06:00 [medline] AID - S0197-4572(13)00252-8 [pii] AID - 10.1016/j.gerinurse.2013.07.003 [doi] PST - ppublish SO - Geriatr Nurs. 2013 Nov-Dec;34(6):457-64. doi: 10.1016/j.gerinurse.2013.07.003. Epub 2013 Aug 22.