PMID- 23980621
OWN - NLM
STAT- MEDLINE
DCOM- 20140519
LR  - 20131004
IS  - 1532-950X (Electronic)
IS  - 0161-3499 (Linking)
VI  - 42
IP  - 7
DP  - 2013 Oct
TI  - Acute adverse events associated with ventral slot decompression in 546 dogs with 
      cervical intervertebral disc disease.
PG  - 795-806
LID - 10.1111/j.1532-950X.2013.12039.x [doi]
AB  - OBJECTIVE: To report the frequency, types, and risk factors for acute 
      perioperative adverse events (AEs) in dogs that had ventral slot decompression 
      (VSD) for cervical intervertebral disc disease (IVDD). DESIGN: Retrospective, 
      case-control study. ANIMALS: Dogs (n = 546) with cervical IVDD treated by VSD; 54 
      cases experiencing AE and 492 controls. METHODS: Historical, clinical, 
      diagnostic, operative, and outcome data were collected. AE were graded using a 
      Spine Adverse Events Severity (SAVES) system. Associations between the 
      development of AE and hypothesized risk factors were analyzed using bi- and 
      multi-variable analyses. RESULTS: AE were observed in 54 dogs (9.9%). Minor AE 
      (SAVES Grade 1-2) occurred in 3.5% (19 dogs) and major (SAVES Grades 3-5) AE in 
      6.4% (35 dogs). Deterioration in neurologic status (n = 13), persistent pain 
      (12), and intraoperative hemorrhage (7) were common major AE. NSAID 
      administration, surgeon experience, C7-T1 disc location, and intraoperative 
      hypotension were significantly associated with AE in multivariate analyses. 
      Improvement of AE occurred in 48/54 (88.9%) of cases, although reoperative 
      neurosurgery was required in 48.5% (17/35) of dogs experiencing major AE. Dogs 
      with major AE had significantly longer hospitalization and worse outcomes than 
      dogs with minor AE or controls. No fatal AE occurred, although 0.7% (4/546) of 
      dogs were euthanatized postoperatively. CONCLUSIONS: AE occurred in 9.9% of dogs 
      that had VSD, and were significantly associated with perioperative hypotension, 
      C7-T1 disc extrusions, surgeon experience, and NSAID usage. Identification of a 
      major postoperative AE is an indication for immediate diagnostic imaging studies, 
      as 50% of dogs experiencing major AE required reoperation.
CI  - (c) Copyright 2013 by The American College of Veterinary Surgeons.
FAU - Rossmeisl, John H Jr
AU  - Rossmeisl JH Jr
AD  - Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College 
      of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia.
FAU - White, Courtney
AU  - White C
FAU - Pancotto, Theresa E
AU  - Pancotto TE
FAU - Bays, Alicia
AU  - Bays A
FAU - Henao-Guerrero, P Natalia
AU  - Henao-Guerrero PN
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130823
PL  - United States
TA  - Vet Surg
JT  - Veterinary surgery : VS
JID - 8113214
SB  - IM
MH  - Animals
MH  - Case-Control Studies
MH  - Cervical Vertebrae/surgery
MH  - Decompression, Surgical/adverse effects/*veterinary
MH  - Dog Diseases/*surgery
MH  - Dogs
MH  - Female
MH  - Intervertebral Disc Displacement/surgery/*veterinary
MH  - Male
MH  - Postoperative Complications/*veterinary
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
EDAT- 2013/08/29 06:00
MHDA- 2014/05/20 06:00
CRDT- 2013/08/29 06:00
PHST- 2013/02/01 00:00 [received]
PHST- 2013/06/01 00:00 [accepted]
PHST- 2013/08/29 06:00 [entrez]
PHST- 2013/08/29 06:00 [pubmed]
PHST- 2014/05/20 06:00 [medline]
AID - 10.1111/j.1532-950X.2013.12039.x [doi]
PST - ppublish
SO  - Vet Surg. 2013 Oct;42(7):795-806. doi: 10.1111/j.1532-950X.2013.12039.x. Epub 
      2013 Aug 23.