PMID- 23990026
OWN - NLM
STAT- MEDLINE
DCOM- 20140929
LR  - 20211021
IS  - 1434-9949 (Electronic)
IS  - 0770-3198 (Linking)
VI  - 33
IP  - 1
DP  - 2014 Jan
TI  - Acute gouty arthritis complicated with acute ST elevation myocardial infarction 
      is independently associated with short- and long-term adverse non-fatal cardiac 
      events.
PG  - 91-8
LID - 10.1007/s10067-013-2376-2 [doi]
AB  - Large epidemiologic studies have associated gouty arthritis with the risk of 
      coronary heart disease. However, there has been a lack of information regarding 
      the outcomes for patients who have gout attacks during hospitalization for acute 
      myocardial infarction. We reviewed the data of 444 consecutive patients who were 
      admitted to our hospital between 2005 and 2008 due to acute ST elevation 
      myocardial infarction (STEMI). The clinical outcomes were compared between 
      patients with gout attack and those without. Of the 444, 48 patients with acute 
      STEMI developed acute gouty arthritis during hospitalization. The multivariate 
      analysis identified prior history of gout and estimated glomerular filtration 
      rate as independent risk factors of gout attack for patients with acute STEMI 
      (odds ratio (OR) 21.02, 95 % CI 2.96-149.26, p = 0.002; OR 0.92, 95 % CI 
      0.86-0.99, p = 0.035, respectively). The in-hospital mortality and duration of 
      hospital stay did not differ significantly between the gouty group and the 
      non-gouty group (controls). During a mean follow-up of 49 +/- 28 months, all-cause 
      mortality and stroke were similar for both groups. Multivariate Cox regression 
      showed that gout attack was independently associated with short- and long-term 
      adverse non-fatal cardiac events (hazard ratio (HR) 1.88, 95 % CI 1.09-3.24, 
      p = 0.024; HR 1.82, 95 % CI 1.09-3.03, p = 0.022, respectively). Gout attack 
      among patients hospitalized due to acute STEMI was independently associated with 
      short-term and long-term rates of adverse non-fatal cardiac events.
FAU - Liu, Kuan-Liang
AU  - Liu KL
AD  - First Cardiovascular Division, Department of Internal Medicine, Chang Gung 
      Memorial Hospital, Chang Gung University College of Medicine, No. 199, Tung-Hwa 
      North Road, Taipei, Taiwan.
FAU - Lee, Hsin-Fu
AU  - Lee HF
FAU - Chou, Shing-Hsien
AU  - Chou SH
FAU - Lin, Yen-Chen
AU  - Lin YC
FAU - Lin, Chia-Pin
AU  - Lin CP
FAU - Wang, Chun-Li
AU  - Wang CL
FAU - Chang, Chi-Jen
AU  - Chang CJ
FAU - Hsu, Lung-An
AU  - Hsu LA
LA  - eng
PT  - Journal Article
DEP - 20130830
PL  - Germany
TA  - Clin Rheumatol
JT  - Clinical rheumatology
JID - 8211469
SB  - IM
MH  - Aged
MH  - Arthritis, Gouty/complications/*diagnosis
MH  - Female
MH  - Glomerular Filtration Rate
MH  - Heart Diseases/complications/mortality
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Myocardial Infarction/complications/*diagnosis
MH  - Odds Ratio
MH  - Proportional Hazards Models
MH  - Regression Analysis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2013/08/31 06:00
MHDA- 2014/09/30 06:00
CRDT- 2013/08/31 06:00
PHST- 2012/11/18 00:00 [received]
PHST- 2013/08/18 00:00 [accepted]
PHST- 2013/07/15 00:00 [revised]
PHST- 2013/08/31 06:00 [entrez]
PHST- 2013/08/31 06:00 [pubmed]
PHST- 2014/09/30 06:00 [medline]
AID - 10.1007/s10067-013-2376-2 [doi]
PST - ppublish
SO  - Clin Rheumatol. 2014 Jan;33(1):91-8. doi: 10.1007/s10067-013-2376-2. Epub 2013 
      Aug 30.