PMID- 23993600
OWN - NLM
STAT- MEDLINE
DCOM- 20140328
LR  - 20191210
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 141
IP  - 4
DP  - 2013 Dec 15
TI  - Validation (in-house and collaboratory) of the quantification method for ethyl 
      carbamate in alcoholic beverages and soy sauce by GC-MS.
PG  - 4161-5
LID - S0308-8146(13)00905-9 [pii]
LID - 10.1016/j.foodchem.2013.06.128 [doi]
AB  - A method for ethyl carbamate (EC) determination in alcoholic beverages and soy 
      sauce was developed by GC-MS. We adopted the diatomaceous earth solid-phase 
      extraction (SPE) column and elution solvent of ethyl acetate/diethyl ether (5:95 
      v/v) for sample cleaning. The in-house validation showed the limit of 
      quantification (LOQ) was 5.0 mug/kg. In the accuracy assay, the total average 
      recovery for was 96.7%. The relative standard deviations (RSDs) were <5%. 
      Subsequently, a collaborative trial was organized for the further validation. The 
      RSDs for repeatability and reproducibility were 1.2-7.8% and 2.3-9.6% 
      respectively. It indicated that the present method performed well in different 
      laboratories.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Huang, Zhu
AU  - Huang Z
AD  - Department of Ophthalmology, The First Affiliated Hospital, College of Medicine, 
      Zhejiang University, Hangzhou, China.
FAU - Pan, Xiao-Dong
AU  - Pan XD
FAU - Wu, Ping-Gu
AU  - Wu PG
FAU - Chen, Qing
AU  - Chen Q
FAU - Han, Jian-Long
AU  - Han JL
FAU - Shen, Xiang-Hong
AU  - Shen XH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20130704
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 3IN71E75Z5 (Urethane)
SB  - IM
MH  - Alcoholic Beverages/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Solid Phase Extraction
MH  - Soy Foods/*analysis
MH  - Urethane/*analysis/isolation & purification
OTO - NOTNLM
OT  - Collaboratory study
OT  - Ethyl carbamate
OT  - Fermented foods
OT  - GC-MS
OT  - Solid-phase extraction
EDAT- 2013/09/03 06:00
MHDA- 2014/03/29 06:00
CRDT- 2013/09/03 06:00
PHST- 2012/11/28 00:00 [received]
PHST- 2013/05/20 00:00 [revised]
PHST- 2013/06/26 00:00 [accepted]
PHST- 2013/09/03 06:00 [entrez]
PHST- 2013/09/03 06:00 [pubmed]
PHST- 2014/03/29 06:00 [medline]
AID - S0308-8146(13)00905-9 [pii]
AID - 10.1016/j.foodchem.2013.06.128 [doi]
PST - ppublish
SO  - Food Chem. 2013 Dec 15;141(4):4161-5. doi: 10.1016/j.foodchem.2013.06.128. Epub 
      2013 Jul 4.