PMID- 23995110
OWN - NLM
STAT- MEDLINE
DCOM- 20140326
LR  - 20191112
IS  - 1880-9952 (Electronic)
IS  - 1346-4280 (Linking)
VI  - 53
IP  - 2
DP  - 2013
TI  - Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) with hemophagocytosis 
      (HPS): successful treatment using high-dose chemotherapy (BFM-NHL & ALL-90) and 
      autologous peripheral blood stem cell transplantation.
PG  - 135-40
AB  - Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare form of 
      non-Hodgkin lymphoma, in which lymphoma cells infiltrate preferentially into 
      subcutaneous adipose tissue. Although various treatment trials for SPTCL have 
      been attempted, no standardized therapy has been established. Here, we report a 
      case of alpha/beta(+) T-cell-phenotype SPTCL (SPTCL-AB) with hemophagocytosis (HPS) in a 
      14-year-old girl, who presented with low-grade fever, general fatigue and chest 
      swelling. Laboratory examinations revealed leukocytopenia, and bone marrow 
      aspiration cytology showed HPS. The diagnosis of SPTCL-AB was made by biopsy on 
      the basis of thickened subcutaneous tissue in the chest wall. Following high-dose 
      chemotherapy (HDT) of BFM-NHL & ALL-90, autologous peripheral blood stem cell 
      transplantation (auto-PBSCT) was performed. The patient responded to the 
      treatment and has remained asymptomatic for 2 years. Our results suggest that a 
      combination of HDT of BFM-NHL & ALL-90 and auto-SCT treatment is effective for 
      SPTCL associated with HPS.
FAU - Sakurai, Eiichi
AU  - Sakurai E
AD  - Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, 
      Japan. sakkuei@iwate-med.ac.jp
FAU - Satoh, Takashi
AU  - Satoh T
FAU - Akiko, Yashima-Abo
AU  - Akiko YA
FAU - Maesawa, Chihaya
AU  - Maesawa C
FAU - Tsunoda, Kanako
AU  - Tsunoda K
FAU - Endo, Mikiya
AU  - Endo M
FAU - Akasaka, Toshihide
AU  - Akasaka T
FAU - Masuda, Tomoyuki
AU  - Masuda T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - J Clin Exp Hematop
JT  - Journal of clinical and experimental hematopathology : JCEH
JID - 101141257
RN  - Subcutaneous panniculitis-like T-cell lymphoma
SB  - IM
MH  - Adolescent
MH  - Antineoplastic Combined Chemotherapy Protocols/therapeutic use
MH  - Biopsy
MH  - Bone Marrow/immunology/pathology
MH  - Cytophagocytosis/*immunology
MH  - Female
MH  - Humans
MH  - Lymphocytes, Tumor-Infiltrating/immunology/metabolism
MH  - Lymphoma, T-Cell/diagnosis/*immunology/therapy
MH  - Magnetic Resonance Imaging
MH  - Panniculitis/diagnosis/*immunology/therapy
MH  - Peripheral Blood Stem Cell Transplantation
MH  - Skin/pathology
MH  - Transplantation, Autologous
EDAT- 2013/09/03 06:00
MHDA- 2014/03/29 06:00
CRDT- 2013/09/03 06:00
PHST- 2013/09/03 06:00 [entrez]
PHST- 2013/09/03 06:00 [pubmed]
PHST- 2014/03/29 06:00 [medline]
AID - DN/JST.JSTAGE/jslrt/53.135 [pii]
AID - 10.3960/jslrt.53.135 [doi]
PST - ppublish
SO  - J Clin Exp Hematop. 2013;53(2):135-40. doi: 10.3960/jslrt.53.135.