PMID- 23996116
OWN - NLM
STAT- MEDLINE
DCOM- 20140619
LR  - 20211021
IS  - 1867-108X (Electronic)
IS  - 1867-1071 (Linking)
VI  - 31
IP  - 10
DP  - 2013 Oct
TI  - MRI differentiation of cardiomyopathy showing left ventricular hypertrophy and 
      heart failure: differentiation between cardiac amyloidosis, hypertrophic 
      cardiomyopathy, and hypertensive heart disease.
PG  - 693-700
LID - 10.1007/s11604-013-0238-0 [doi]
AB  - PURPOSE: To evaluate the capability of MRI to differentiate cardiac amyloidosis 
      (CA), end-stage hypertrophic cardiomyopathy (HCM), and hypertensive heart disease 
      (HHD), which are important etiologies of left ventricular hypertrophy (LVH) and 
      heart failure. MATERIALS AND METHODS: We enrolled 26 patients presenting with 
      both LVH and heart failure: six with CA, nine with end-stage HCM, and 11 with 
      HHD. Cardiac function, presence of pericardial or pleural effusion, and the 
      extent and patterns of late gadolinium enhancement (LGE) were compared among the 
      three diseases. RESULTS: Myocardial LGE was observed in all six CA patients, 
      eight end-stage HCM patients, and six HHD patients. The number of LGE segments 
      was significantly greater in CA than in HCM or HHD (p = 0.02 for both), and all 
      patients with CA showed a global endocardial pattern of LGE. There were 
      significant differences among CA, HCM, and HHD in ejection fraction and 
      end-diastolic and end-systolic volume indices (p < 0.05 for all). Pericardial 
      effusion was observed more frequently in CA than in HCM or HHD (p = 0.04 or 0.01, 
      respectively). CONCLUSION: MRI is valuable for distinguishing among CA, end-stage 
      HCM, and HHD, all of which present with LVH and heart failure.
FAU - Takeda, Minako
AU  - Takeda M
AD  - Department of Radiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 
      113-8603, Japan, minako11191982@nms.ac.jp.
FAU - Amano, Yasuo
AU  - Amano Y
FAU - Tachi, Masaki
AU  - Tachi M
FAU - Tani, Hitomi
AU  - Tani H
FAU - Mizuno, Kyoichi
AU  - Mizuno K
FAU - Kumita, Shinichiro
AU  - Kumita S
LA  - eng
PT  - Journal Article
DEP - 20130831
PL  - Japan
TA  - Jpn J Radiol
JT  - Japanese journal of radiology
JID - 101490689
RN  - 0 (Contrast Media)
RN  - 84F6U3J2R6 (gadodiamide)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Amyloidosis/diagnosis
MH  - Biopsy
MH  - Cardiomyopathy, Hypertrophic/diagnosis
MH  - Contrast Media
MH  - Diagnosis, Differential
MH  - Female
MH  - Gadolinium DTPA
MH  - Heart Diseases/*diagnosis
MH  - Heart Failure/diagnosis
MH  - Humans
MH  - Hypertension/diagnosis
MH  - Hypertrophy, Left Ventricular/diagnosis
MH  - Image Interpretation, Computer-Assisted
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
EDAT- 2013/09/03 06:00
MHDA- 2014/06/20 06:00
CRDT- 2013/09/03 06:00
PHST- 2013/04/22 00:00 [received]
PHST- 2013/08/14 00:00 [accepted]
PHST- 2013/09/03 06:00 [entrez]
PHST- 2013/09/03 06:00 [pubmed]
PHST- 2014/06/20 06:00 [medline]
AID - 10.1007/s11604-013-0238-0 [doi]
PST - ppublish
SO  - Jpn J Radiol. 2013 Oct;31(10):693-700. doi: 10.1007/s11604-013-0238-0. Epub 2013 
      Aug 31.