PMID- 23998547
OWN - NLM
STAT- MEDLINE
DCOM- 20140624
LR  - 20131025
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 168
IP  - 6
DP  - 2013 Oct 15
TI  - Left circumflex artery-related myocardial infarction: does ST elevation matter? 
      Results from the Euro Heart Survey PCI registry.
PG  - 5239-42
LID - S0167-5273(13)01549-0 [pii]
LID - 10.1016/j.ijcard.2013.08.024 [doi]
AB  - BACKGROUND/OBJECTIVES: Little is known about angiographic and clinical 
      differences in patients presenting with left circumflex artery (LCX)-related ST 
      elevation myocardial infarction (STEMI) and non ST elevation myocardial 
      infarction (NSTEMI). We sought to determine the clinical significance of ST 
      elevations in patients with LCX-related myocardial infarction. METHODS AND 
      RESULTS: Between 2005 and 2008 10,503 consecutive patients with acute STEMI and 
      NSTEMI undergoing percutaneous coronary intervention (PCI) were prospectively 
      enrolled into the Euro Heart Survey PCI-Registry. For the present analysis 
      patients with LCX-related STEMI (n=1100, 54.7%) were compared to those with 
      LCX-related NSTEMI (n=910, 45.3%). NSTEMI-patients were older, more often female 
      and had a higher incidence of prior cardiac events. Patients with STEMI more 
      frequently presented with shock (8.0 versus 3.9%, P<0.001) or had been 
      resuscitated (8.5 versus 2.7%, P<0.0001). TIMI 0-1 before PCI was much more often 
      found among those with STEMI (58.2 versus 25.1%, P<0.0001). In the univariate 
      analysis there were no significant differences in hospital mortality (STEMI: 
      4.8%, NSTEMI: 3.5%, P=0.17), however after adjustment for age, female gender, 
      diabetes and chronic renal failure hospital mortality was significantly higher in 
      STEMI patients (odds ratio 1.71, 95%-CI 1.08-2.72, P<0.05). CONCLUSIONS: Over 50% 
      of the patients with LCX-related myocardial infarction treated with PCI had ST 
      elevations in the initial electrocardiogram. STEMIs were more often associated 
      with total vessel occlusions or haemodynamic instability. In-hospital mortality 
      was significantly higher in patients with LCX-related STEMI.
CI  - (c) 2013.
FAU - Bauer, Timm
AU  - Bauer T
AD  - Herzzentrum Ludwigshafen, Institut fur Herzinfarktforschung Ludwigshafen, 
      Germany; Universitatsklinik Giessen, Germany. Electronic address: 
      bauer-timm@gmx.de.
FAU - Gitt, Anselm K
AU  - Gitt AK
FAU - Hochadel, Matthias
AU  - Hochadel M
FAU - Mollmann, Helge
AU  - Mollmann H
FAU - Nef, Holger
AU  - Nef H
FAU - Weidinger, Franz
AU  - Weidinger F
FAU - Zahn, Ralf
AU  - Zahn R
FAU - Hamm, Christian W
AU  - Hamm CW
FAU - Marco, Jean
AU  - Marco J
FAU - Zeymer, Uwe
AU  - Zeymer U
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20130814
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Angina Pectoris/diagnosis/mortality/therapy
MH  - *Coronary Vessels
MH  - Data Collection
MH  - Electrocardiography
MH  - Europe/epidemiology
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/*mortality/therapy
MH  - Percutaneous Coronary Intervention/*mortality
MH  - Prospective Studies
MH  - Registries
MH  - Risk Factors
MH  - Time-to-Treatment/statistics & numerical data
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Left circumflex artery
OT  - Non ST elevation myocardial infarction
OT  - Percutaneous coronary intervention
OT  - ST elevation myocardial infarction
EDAT- 2013/09/04 06:00
MHDA- 2014/06/25 06:00
CRDT- 2013/09/04 06:00
PHST- 2013/05/27 00:00 [received]
PHST- 2013/07/20 00:00 [revised]
PHST- 2013/08/03 00:00 [accepted]
PHST- 2013/09/04 06:00 [entrez]
PHST- 2013/09/04 06:00 [pubmed]
PHST- 2014/06/25 06:00 [medline]
AID - S0167-5273(13)01549-0 [pii]
AID - 10.1016/j.ijcard.2013.08.024 [doi]
PST - ppublish
SO  - Int J Cardiol. 2013 Oct 15;168(6):5239-42. doi: 10.1016/j.ijcard.2013.08.024. 
      Epub 2013 Aug 14.