PMID- 24006356
OWN - NLM
STAT- MEDLINE
DCOM- 20140909
LR  - 20220309
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Linking)
VI  - 39
IP  - 1
DP  - 2014 Jan
TI  - Three-dimensional late gadolinium-enhanced MR imaging of the left atrium: a 
      comparison of spiral versus Cartesian k-space trajectories.
PG  - 211-6
LID - 10.1002/jmri.24146 [doi]
AB  - PURPOSE: To investigate the feasibility of high-resolution late gadolinium 
      enhancement (LGE) imaging using a three-dimensional (3D) stack of spirals k-space 
      trajectory for the detection of left atrial (LA) ablation lesions. LGE imaging 
      inherently suffers from low SNR, so that improvements in spatial resolution and 
      imaging time are challenging. The spiral trajectory offers greater acquisition 
      efficiency, and this is used for increased spatial resolution. MATERIALS AND 
      METHODS: Nine healthy subjects and 10 pre/post pulmonary vein isolation patients 
      underwent an MRI examination. A Cartesian 3D inversion-recovery gradient-echo 
      sequence was performed followed by a 3D inversion-recovery gradient-echo with a 
      spiral trajectory. Image quality, fat suppression and sharpness were graded by 
      expert cardiologists. RESULTS: No statistical significance was determined for SNR 
      or image quality between the Cartesian and spiral images; however, fat 
      suppression was significantly improved with the spiral approach (P = 0.002). The 
      enhancement in the Cartesian scan was found to have significantly higher CNR 
      (P = 0.02). CONCLUSION: The feasibility of spiral LGE in the left atrium has been 
      demonstrated. Similar image quality and sharpness were observed with both 
      acquisitions. This spiral sequence has sub-millimeter spatial resolution improved 
      fat suppression and maintains a comparable level of SNR compared with the 
      Cartesian scan.
CI  - Copyright (c) 2013 Wiley Periodicals, Inc.
FAU - Knowles, Benjamin R
AU  - Knowles BR
AD  - Division of Imaging Sciences and Biomedical Engineering, King's College London, 
      London, United Kingdom; Department of Medicine (Cardiovascular Division), Beth 
      Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, 
      USA.
FAU - Peters, Dana C
AU  - Peters DC
FAU - Clough, Rachel E
AU  - Clough RE
FAU - Razavi, Reza
AU  - Razavi R
FAU - Schaeffter, Tobias
AU  - Schaeffter T
FAU - Prieto, Claudia
AU  - Prieto C
LA  - eng
GR  - MR/J006742/1/MRC_/Medical Research Council/United Kingdom
PT  - Comparative Study
PT  - Journal Article
DEP - 20130904
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Aged
MH  - Equipment Design
MH  - Female
MH  - Gadolinium/*chemistry
MH  - Heart Atria/*pathology
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Imaging, Three-Dimensional
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Phantoms, Imaging
MH  - Pulmonary Veins/pathology
MH  - Radio Waves
MH  - Reproducibility of Results
MH  - Signal-To-Noise Ratio
MH  - Time Factors
OTO - NOTNLM
OT  - Cartesian
OT  - late gadolinium enhancement
OT  - left atrium
OT  - spiral
EDAT- 2013/09/06 06:00
MHDA- 2014/09/10 06:00
CRDT- 2013/09/06 06:00
PHST- 2011/09/27 00:00 [received]
PHST- 2013/03/01 00:00 [accepted]
PHST- 2013/09/06 06:00 [entrez]
PHST- 2013/09/06 06:00 [pubmed]
PHST- 2014/09/10 06:00 [medline]
AID - 10.1002/jmri.24146 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2014 Jan;39(1):211-6. doi: 10.1002/jmri.24146. Epub 2013 
      Sep 4.