PMID- 24016452
OWN - NLM
STAT- MEDLINE
DCOM- 20140630
LR  - 20131118
IS  - 1751-732X (Electronic)
IS  - 1751-7311 (Linking)
VI  - 7
IP  - 12
DP  - 2013 Dec
TI  - Microencapsulated sodium selenite supplementation in dairy cows: effects on 
      selenium status.
PG  - 1944-9
LID - 10.1017/S1751731113001547 [doi]
AB  - The objective of this study was to compare the efficiency of transfer of selenium 
      (Se) to plasma and milk from inorganic sodium selenite, either free or 
      microencapsulated, and from selenized yeast in dairy cows. The study consisted of 
      an in situ-nylon bags incubation, and in an in vivo experiment to compare the Se 
      status of cows supplemented with either sodium selenite, microencapsulated sodium 
      selenite, or Se yeast. Thirty dairy cows, divided in five groups, were fed the 
      following diets: the control group (CTR) received a total mixed ration 
      supplemented with sodium selenite in order to have 0.3 mg/kg DM of total Se; 0.3M 
      and 0.5M groups received the same control diet supplemented with lipid 
      microencapsulated sodium selenite to provide 0.3 and 0.5 mg/kg DM of total Se, 
      respectively; 0.3Y and 0.5Y groups received selenized yeast to provide 0.3 and 
      0.5 mg/kg of total Se, respectively. Cows were fed the supplements for 56 days 
      during which milk, blood, and fecal samples were collected weekly to conduct 
      analysis of Se and glutathione peroxidase (GSH-px) activity. Se concentration in 
      the nylon bags was assessed to 72%, 64%, and 40% of the initial value (time 0) 
      after 4, 8, and 24 h of incubation, respectively. In vivo, cows supplemented with 
      0.3 mg/kg of microencapsulated Se had higher milk Se concentration compared to 
      CTR. The increment was more pronounced at the highest inclusion rate (0.5 mg/kg, 
      0.5M group). GSH-px activity was not significantly affected by treatments. The 
      results indicate that lipid microencapsulation has the potential to protect 
      nutrients from complete rumen reduction and that Se from microencapsulated 
      selenite is incorporated in milk more efficiently than the free form. 
      Microencapsulated sodium selenite was shown to be comparable to Se-yeast in terms 
      of availability and incorporation in milk when fed at 0.3 mg/kg DM, whereas the 
      inclusion in the diet at 0.5 mg/kg DM resulted in higher plasma and milk 
      concentrations than selenized yeast.
FAU - Grilli, E
AU  - Grilli E
AD  - 1 Dipartimento di Scienze Mediche Veterinarie, Universita di Bologna, Bologna 
      40064, Italy.
FAU - Gallo, A
AU  - Gallo A
FAU - Fustini, M
AU  - Fustini M
FAU - Fantinati, P
AU  - Fantinati P
FAU - Piva, A
AU  - Piva A
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20130910
PL  - England
TA  - Animal
JT  - Animal : an international journal of animal bioscience
JID - 101303270
RN  - H6241UJ22B (Selenium)
RN  - HIW548RQ3W (Sodium Selenite)
SB  - IM
MH  - Animal Feed/analysis
MH  - Animal Nutritional Physiological Phenomena
MH  - Animals
MH  - Cattle/blood/*physiology
MH  - Diet/veterinary
MH  - Dietary Supplements
MH  - Drug Compounding
MH  - Feces/chemistry
MH  - Female
MH  - Milk/chemistry
MH  - Selenium/*blood/chemistry
MH  - Sodium Selenite/chemistry/*pharmacology
EDAT- 2013/09/11 06:00
MHDA- 2014/07/01 06:00
CRDT- 2013/09/11 06:00
PHST- 2013/09/11 06:00 [entrez]
PHST- 2013/09/11 06:00 [pubmed]
PHST- 2014/07/01 06:00 [medline]
AID - S1751731113001547 [pii]
AID - 10.1017/S1751731113001547 [doi]
PST - ppublish
SO  - Animal. 2013 Dec;7(12):1944-9. doi: 10.1017/S1751731113001547. Epub 2013 Sep 10.