PMID- 24019776 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20130910 LR - 20211021 IS - 1662-6567 (Print) IS - 1662-6567 (Electronic) IS - 1662-6567 (Linking) VI - 5 IP - 2 DP - 2013 TI - Subacute cutaneous lupus erythematosus triggered by radiotherapy. PG - 232-6 LID - 10.1159/000354721 [doi] AB - BACKGROUND: The origin of collagen autoimmune diseases is not fully understood. Some studies postulate a mechanism of molecular mimicry or heterologous immunity following viral infections triggering autoimmunity. Apart from infections, other exogenous factors such as visible light or X-rays have been reported to incite autoimmunity. CASE REPORT: We report a case of histologically and serologically confirmed subacute lupus erythematosus (SCLE) following radiotherapy for breast cancer. DISCUSSION: The close temporal and spatial correlation between radiotherapy and onset of SCLE in this patient suggests that an autoimmune reaction may have been triggered locally by functionally altering the immune system and breaking self-tolerance. FAU - Kolm, I AU - Kolm I AD - Department of Dermatology, University Hospital Zurich, Zurich, Switzerland. FAU - Pawlik, E AU - Pawlik E FAU - Eggmann, N AU - Eggmann N FAU - Kamarachev, J AU - Kamarachev J FAU - Kerl, K AU - Kerl K FAU - French, L E AU - French LE FAU - Hofbauer, G F L AU - Hofbauer GF LA - eng PT - Case Reports DEP - 20130817 PL - Switzerland TA - Case Rep Dermatol JT - Case reports in dermatology JID - 101517685 PMC - PMC3764944 OTO - NOTNLM OT - Autoimmune reaction OT - Autoimmunity OT - Lupus erythematosus OT - Radiotherapy EDAT- 2013/09/11 06:00 MHDA- 2013/09/11 06:01 PMCR- 2013/08/17 CRDT- 2013/09/11 06:00 PHST- 2013/09/11 06:00 [entrez] PHST- 2013/09/11 06:00 [pubmed] PHST- 2013/09/11 06:01 [medline] PHST- 2013/08/17 00:00 [pmc-release] AID - cde-0005-0232 [pii] AID - 10.1159/000354721 [doi] PST - epublish SO - Case Rep Dermatol. 2013 Aug 17;5(2):232-6. doi: 10.1159/000354721. eCollection 2013.