PMID- 24020019
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130910
LR  - 20220310
IS  - 2233-7903 (Print)
IS  - 2093-0488 (Electronic)
IS  - 1226-0053 (Linking)
VI  - 85
IP  - 3
DP  - 2013 Sep
TI  - The effect of duodenojejunal bypass for type 2 diabetes mellitus patients below 
      body mass index 25 kg/m(2): one year follow-up.
PG  - 109-15
LID - 10.4174/jkss.2013.85.3.109 [doi]
AB  - PURPOSE: The goals of this study are to evaluate the effect of duodenojejunal 
      bypass (DJB) for type 2 diabetes mellitus (T2DM) patients below body mass index 
      (BMI) 25 kg/m(2) in one year follow-up, and to compare the results of 1 week 
      which we have reported in 2011. METHODS: In this prospective observational study, 
      there were 31 type 2 diabetic patients who underwent DJB at Inha University 
      Hospital from July 2009 to January 2011. We did laboratories such as 75-g oral 
      glucose tolerance test (OGTT), insulin level and hemoglobin A1c (HbA1c), etc. and 
      compared their changes of preoperative, a week, 3 months, and 12 months. RESULTS: 
      Mean BMI was 23.1 +/- 1.3 kg/m(2), mean duration of T2DM was 8.3 +/- 4.7 and mean age 
      was 46.6 +/- 7.7 years. There were a significant decrease of 75-g OGTT levels and 
      increase of insulin secretion after 3 months. 13.3% showed diabetic remission 
      (HbA1c < 6.0, medication cessation) and 26.7% showed diabetic improvement. The 
      rates of remission and improvement much declined comparing with that of 
      postoperative 1 week although those were determined by fasting and postprandial 2 
      hour level of glucose. CONCLUSION: This is the first study of metabolic surgery 
      in Korean diabetes patients in the healthy weight range. DJB exerted positive 
      influences on insulin resistance as well as beta cell function. Early effects on 
      T2DM after DJB could be estimated as one of good modalities, although the 
      effectiveness seems to be unacceptable. Further studies are mandatory for 
      evaluation of the effectiveness of metabolic surgery and finding prognostic 
      factors.
FAU - Heo, Yoonseok
AU  - Heo Y
AD  - Department of Surgery, Inha University School of Medicine, Incheon, Korea.
FAU - Ahn, Jong-Hyuk
AU  - Ahn JH
FAU - Shin, Seok-Hwan
AU  - Shin SH
FAU - Lee, Yeon-Ji
AU  - Lee YJ
LA  - eng
PT  - Journal Article
DEP - 20130826
PL  - Korea (South)
TA  - J Korean Surg Soc
JT  - Journal of the Korean Surgical Society
JID - 101564795
PMC - PMC3764361
OTO - NOTNLM
OT  - Duodenojejunal bypass
OT  - Metabolic surgery
OT  - Type 2 diabetes mellitus
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2013/09/11 06:00
MHDA- 2013/09/11 06:01
PMCR- 2013/09/01
CRDT- 2013/09/11 06:00
PHST- 2013/03/26 00:00 [received]
PHST- 2013/05/13 00:00 [revised]
PHST- 2013/05/27 00:00 [accepted]
PHST- 2013/09/11 06:00 [entrez]
PHST- 2013/09/11 06:00 [pubmed]
PHST- 2013/09/11 06:01 [medline]
PHST- 2013/09/01 00:00 [pmc-release]
AID - 10.4174/jkss.2013.85.3.109 [doi]
PST - ppublish
SO  - J Korean Surg Soc. 2013 Sep;85(3):109-15. doi: 10.4174/jkss.2013.85.3.109. Epub 
      2013 Aug 26.