PMID- 24021389 OWN - NLM STAT- MEDLINE DCOM- 20140703 LR - 20131104 IS - 1873-3379 (Electronic) IS - 0891-4222 (Linking) VI - 34 IP - 11 DP - 2013 Nov TI - The ex-Gaussian distribution of reaction times in adolescents with attention-deficit/hyperactivity disorder. PG - 3709-19 LID - S0891-4222(13)00326-0 [pii] LID - 10.1016/j.ridd.2013.07.025 [doi] AB - We investigated the three parameters (mu, sigma, tau) of ex-Gaussian distribution of RT derived from the Conners' continuous performance test (CCPT) and examined the moderating effects of the energetic factors (the inter-stimulus intervals (ISIs) and Blocks) among these three parameters, especially tau, an index describing the positive skew of RT distribution. We assessed 195 adolescents with DSM-IV ADHD, and 90 typically developing (TD) adolescents, aged 10-16. Participants and their parents received psychiatric interviews to confirm the diagnosis of ADHD and other psychiatric disorders. Participants also received intelligence (WISC-III) and CCPT assessments. We found that participants with ADHD had a smaller mu, and larger tau. As the ISI/Block increased, the magnitude of group difference in tau increased. Among the three ex-Gaussian parameters, tau was positively associated with omission errors, and mu was negatively associated with commission errors. The moderating effects of ISIs and Blocks on tau parameters suggested that the ex-Gaussian parameters could offer more information about the attention state in vigilance task, especially in ADHD. CI - Copyright (c) 2013 Elsevier Ltd. All rights reserved. FAU - Gu, Shoou-Lian Hwang AU - Gu SL AD - Graduate Institute of Behavioral Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan. FAU - Gau, Susan Shur-Fen AU - Gau SS FAU - Tzang, Shyh-Weir AU - Tzang SW FAU - Hsu, Wen-Yau AU - Hsu WY LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130907 PL - United States TA - Res Dev Disabil JT - Research in developmental disabilities JID - 8709782 SB - IM MH - Adolescent MH - Attention/physiology MH - Attention Deficit Disorder with Hyperactivity/*physiopathology MH - Case-Control Studies MH - Child MH - Female MH - Humans MH - Male MH - Neuropsychological Tests MH - Normal Distribution MH - Reaction Time/*physiology OTO - NOTNLM OT - ADHD OT - Cognitive-energetic model OT - Effort allocation OT - Ex-Gaussian distribution OT - Reaction time variability EDAT- 2013/09/12 06:00 MHDA- 2014/07/06 06:00 CRDT- 2013/09/12 06:00 PHST- 2013/05/23 00:00 [received] PHST- 2013/07/16 00:00 [revised] PHST- 2013/07/17 00:00 [accepted] PHST- 2013/09/12 06:00 [entrez] PHST- 2013/09/12 06:00 [pubmed] PHST- 2014/07/06 06:00 [medline] AID - S0891-4222(13)00326-0 [pii] AID - 10.1016/j.ridd.2013.07.025 [doi] PST - ppublish SO - Res Dev Disabil. 2013 Nov;34(11):3709-19. doi: 10.1016/j.ridd.2013.07.025. Epub 2013 Sep 7.