PMID- 24031815
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130913
LR  - 20211021
IS  - 1517-8382 (Print)
IS  - 1678-4405 (Electronic)
IS  - 1517-8382 (Linking)
VI  - 43
IP  - 1
DP  - 2012 Jan
TI  - Influence of phenolic compounds on the growth and arginine deiminase system in a 
      wine lactic acid bacterium.
PG  - 167-76
LID - 10.1590/S1517-838220120001000018 [doi]
AB  - The influence of seven phenolic compounds, normally present in wine, on the 
      growth and arginine deiminase system (ADI) of Lactobacillus hilgardii X1B, a wine 
      lactic acid bacterium, was established. This system provides energy for bacterial 
      growth and produces citrulline that reacts with ethanol forming the carcinogen 
      ethyl carbamate (EC), found in some wines. The influence of phenolic compounds on 
      bacterial growth was compound dependent. Growth and final pH values increased in 
      presence of arginine. Arginine consumption decreased in presence of 
      protocatechuic and gallic acids (31 and 17%, respectively) and increased in 
      presence of quercetin, rutin, catechin and the caffeic and vanillic phenolic 
      acids (between 10 and 13%, respectively). ADI enzyme activities varied in 
      presence of phenolic compounds. Rutin, quercetin and caffeic and vanillic acids 
      stimulated the enzyme arginine deiminase about 37-40%. Amounts of 200 mg/L gallic 
      and protocatechuic acids inhibited the arginine deiminase enzyme between 53 and 
      100%, respectively. Ornithine transcarbamylase activity was not modified at all 
      concentrations of phenolic compounds. As gallic and protocatechuic acids 
      inhibited the arginine deiminase enzyme that produces citrulline, precursor of 
      EC, these results are important considering the formation of toxic compounds.
FAU - Alberto, Maria R
AU  - Alberto MR
AD  - Centro Cientifico Tecnologico CCT-CONICET , Tucuman , Argentina.
FAU - de Nadra, Maria C Manca
AU  - de Nadra MC
FAU - Arena, Mario E
AU  - Arena ME
LA  - eng
PT  - Journal Article
DEP - 20120601
PL  - Brazil
TA  - Braz J Microbiol
JT  - Brazilian journal of microbiology : [publication of the Brazilian Society for 
      Microbiology]
JID - 101095924
PMC - PMC3768993
OTO - NOTNLM
OT  - Lactobacillus hilgardii
OT  - arginine
OT  - polyphenols
EDAT- 2012/01/01 00:00
MHDA- 2012/01/01 00:01
PMCR- 2012/02/01
CRDT- 2013/09/14 06:00
PHST- 2010/11/07 00:00 [received]
PHST- 2011/07/01 00:00 [revised]
PHST- 2012/08/30 00:00 [accepted]
PHST- 2013/09/14 06:00 [entrez]
PHST- 2012/01/01 00:00 [pubmed]
PHST- 2012/01/01 00:01 [medline]
PHST- 2012/02/01 00:00 [pmc-release]
AID - S1517-838220120001000018 [pii]
AID - 10.1590/S1517-838220120001000018 [doi]
PST - ppublish
SO  - Braz J Microbiol. 2012 Jan;43(1):167-76. doi: 10.1590/S1517-838220120001000018. 
      Epub 2012 Jun 1.