PMID- 24036419
OWN - NLM
STAT- MEDLINE
DCOM- 20140731
LR  - 20131209
IS  - 1095-8274 (Electronic)
IS  - 1075-9964 (Linking)
VI  - 24
DP  - 2013 Dec
TI  - The effects of stress hormones on growth of selected periodontitis related 
      bacteria.
PG  - 49-54
LID - S1075-9964(13)00142-X [pii]
LID - 10.1016/j.anaerobe.2013.09.001 [doi]
AB  - The focus of this study was to examine in vitro the effects of stress hormones 
      (catecholamines: epinephrine, norepinephrine, dopamine and hydrocortisone: 
      cortisol) on the growth of four anaerobic species of periodontitis-related 
      bacteria (Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella 
      intermedia and Tannerella forsythia) and one facultative anaerobic species 
      (Eikenella corrodens). Bacterial growth was determined by two different methods: 
      fluorescence in situ hybridization (FISH), and the viable count by culture 
      method. To simulate stress, each single strain was grown in a special growth 
      medium with three different concentrations of each hormone, using an anaerobic 
      chamber at 37  degrees C. Growth of F. nucleatum increased in the presence of all stress 
      hormones. Growth of P. gingivalis was not significantly influenced by any 
      hormone. Growth of P. intermedia and E. corrodens was inhibited by almost all 
      stress hormones tested. Both methods of analysis revealed that the highest 
      concentrations of norepinephrine and cortisol increased the growth of T. 
      forsythia. Different hormones have a different effect on the growth of 
      periodontitis-related bacteria in vitro. It appears that bacterial viability is 
      more strongly influenced than is bacterial metabolic activity. The growth of F. 
      nucleatum particularly and partially of T. forsythia is increased by several 
      stress hormones and may have an additional negative impact on periodontal 
      disease.
CI  - Copyright (c) 2013. Published by Elsevier Ltd.
FAU - Jentsch, H F R
AU  - Jentsch HF
AD  - University Hospital of Leipzig, Department of Cariology, Endodontology and 
      Periodontology, Centre for Periodontology, Liebigstr. 12, D-04103, Germany. 
      Electronic address: jenh@medizin.uni-leipzig.de.
FAU - Marz, Diana
AU  - Marz D
FAU - Kruger, Monika
AU  - Kruger M
LA  - eng
PT  - Journal Article
DEP - 20130913
PL  - England
TA  - Anaerobe
JT  - Anaerobe
JID - 9505216
RN  - 0 (Catecholamines)
RN  - 0 (Culture Media)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Anaerobiosis
MH  - Bacteria, Anaerobic/*drug effects/*growth & development
MH  - Catecholamines/*metabolism
MH  - Colony Count, Microbial
MH  - Culture Media/chemistry
MH  - Eikenella corrodens/*drug effects/*growth & development
MH  - Humans
MH  - Hydrocortisone/*metabolism
MH  - In Situ Hybridization, Fluorescence
MH  - Periodontitis/*microbiology
OTO - NOTNLM
OT  - Anaerobe bacteria
OT  - Catecholamine
OT  - Cortisol
OT  - Periodontal disease
OT  - Stress
EDAT- 2013/09/17 06:00
MHDA- 2014/08/01 06:00
CRDT- 2013/09/17 06:00
PHST- 2013/04/29 00:00 [received]
PHST- 2013/08/20 00:00 [revised]
PHST- 2013/09/02 00:00 [accepted]
PHST- 2013/09/17 06:00 [entrez]
PHST- 2013/09/17 06:00 [pubmed]
PHST- 2014/08/01 06:00 [medline]
AID - S1075-9964(13)00142-X [pii]
AID - 10.1016/j.anaerobe.2013.09.001 [doi]
PST - ppublish
SO  - Anaerobe. 2013 Dec;24:49-54. doi: 10.1016/j.anaerobe.2013.09.001. Epub 2013 Sep 
      13.