PMID- 24038366 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20130917 LR - 20160511 IS - 1876-3413 (Print) IS - 1876-3405 (Linking) VI - 3 IP - 3 DP - 2011 Sep TI - Planning schistosomiasis control: investigation of alternative sampling strategies for Schistosoma mansoni to target mass drug administration of praziquantel in East Africa. PG - 165-75 LID - 10.1016/j.inhe.2011.06.002 [doi] AB - In schistosomiasis control, there is a need to geographically target treatment to populations at high risk of morbidity. This paper evaluates alternative sampling strategies for surveys of Schistosoma mansoni to target mass drug administration in Kenya and Ethiopia. Two main designs are considered: lot quality assurance sampling (LQAS) of children from all schools; and a geostatistical design that samples a subset of schools and uses semi-variogram analysis and spatial interpolation to predict prevalence in the remaining unsurveyed schools. Computerized simulations are used to investigate the performance of sampling strategies in correctly classifying schools according to treatment needs and their cost-effectiveness in identifying high prevalence schools. LQAS performs better than geostatistical sampling in correctly classifying schools, but at a cost with a higher cost per high prevalence school correctly classified. It is suggested that the optimal surveying strategy for S. mansoni needs to take into account the goals of the control programme and the financial and drug resources available. FAU - Sturrock, Hugh J W AU - Sturrock HJ AD - Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom. FAU - Gething, Pete W AU - Gething PW FAU - Ashton, Ruth A AU - Ashton RA FAU - Kolaczinski, Jan H AU - Kolaczinski JH FAU - Kabatereine, Narcis B AU - Kabatereine NB FAU - Brooker, Simon AU - Brooker S LA - eng PT - Journal Article PL - England TA - Int Health JT - International health JID - 101517095 EDAT- 2011/09/01 00:00 MHDA- 2011/09/01 00:01 CRDT- 2013/09/17 06:00 PHST- 2013/09/17 06:00 [entrez] PHST- 2011/09/01 00:00 [pubmed] PHST- 2011/09/01 00:01 [medline] AID - j.inhe.2011.06.002 [pii] AID - 10.1016/j.inhe.2011.06.002 [doi] PST - ppublish SO - Int Health. 2011 Sep;3(3):165-75. doi: 10.1016/j.inhe.2011.06.002.