PMID- 24048343 OWN - NLM STAT- MEDLINE DCOM- 20140227 LR - 20211021 IS - 1424-8220 (Electronic) IS - 1424-8220 (Linking) VI - 13 IP - 9 DP - 2013 Sep 17 TI - Model-based spike detection of epileptic EEG data. PG - 12536-47 LID - 10.3390/s130912536 [doi] AB - Accurate automatic spike detection is highly beneficial to clinical assessment of epileptic electroencephalogram (EEG) data. In this paper, a new two-stage approach is proposed for epileptic spike detection. First, the k-point nonlinear energy operator (k-NEO) is adopted to detect all possible spike candidates, then a newly proposed spike model with slow wave features is applied to these candidates for spike classification. Experimental results show that the proposed system, using the AdaBoost classifier, outperforms the conventional method in both two- and three-class EEG pattern classification problems. The proposed system not only achieves better accuracy for spike detection, but also provides new ability to differentiate between spikes and spikes with slow waves. Though spikes with slow waves occur frequently in epileptic EEGs, they are not used in conventional spike detection. Identifying spikes with slow waves allows the proposed system to have better capability for assisting clinical neurologists in routine EEG examinations and epileptic diagnosis. FAU - Liu, Yung-Chun AU - Liu YC AD - Department of Computer Science and Information Engineering, National Cheng Kung University, No. 1, University Road, Tainan City 701, Taiwan. ynsun@mail.ncku.edu.tw. FAU - Lin, Chou-Ching K AU - Lin CC FAU - Tsai, Jing-Jane AU - Tsai JJ FAU - Sun, Yung-Nien AU - Sun YN LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130917 PL - Switzerland TA - Sensors (Basel) JT - Sensors (Basel, Switzerland) JID - 101204366 SB - IM MH - *Action Potentials MH - Algorithms MH - Brain/*physiopathology MH - Computer Simulation MH - Diagnosis, Computer-Assisted/*methods MH - Electroencephalography/*methods MH - Epilepsy/*diagnosis/*physiopathology MH - Humans MH - *Models, Neurological MH - Pattern Recognition, Automated/methods MH - Reproducibility of Results MH - Sensitivity and Specificity PMC - PMC3821325 EDAT- 2013/09/21 06:00 MHDA- 2014/02/28 06:00 PMCR- 2013/09/01 CRDT- 2013/09/20 06:00 PHST- 2013/06/17 00:00 [received] PHST- 2013/09/06 00:00 [revised] PHST- 2013/09/13 00:00 [accepted] PHST- 2013/09/20 06:00 [entrez] PHST- 2013/09/21 06:00 [pubmed] PHST- 2014/02/28 06:00 [medline] PHST- 2013/09/01 00:00 [pmc-release] AID - s130912536 [pii] AID - sensors-13-12536 [pii] AID - 10.3390/s130912536 [doi] PST - epublish SO - Sensors (Basel). 2013 Sep 17;13(9):12536-47. doi: 10.3390/s130912536.