PMID- 24049223 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20130919 LR - 20220318 IS - 0253-7176 (Print) IS - 0975-1564 (Electronic) IS - 0253-7176 (Linking) VI - 35 IP - 2 DP - 2013 Apr TI - Effects of Psychopathology, Functioning and Anti-psychotic Medication Adherence on Caregivers' Burden in Schizophrenia. PG - 135-40 LID - 10.4103/0253-7176.116237 [doi] AB - BACKGROUND: The aim of the study was to determine the effects of the level of psychopathology and anti-psychotic medication adherence on caregivers' burden in schizophrenia. MATERIALS AND METHODS: Three hundred and sixty-seven schizophrenia patient/caregiver dyads were interviewed. Caregiver's burden was assessed using the Yoruba version of the Family Burden Interview Schedule (FBIS) and 12-Item General Health Questionnaire (GHQ-12). Patients were assessed using the Global Assessment of Functioning (GAF) scale, Positive and Negative Symptoms Scale (PANSS), and medication compliance questionnaire. RESULTS: Mean age of the patients was 29.7 SD (8.6) years. About 82% of the 368 caregivers were parents of the patients with mean age of 58.1 years (SD 19.6). Total mean objective FBIS score was 22.69 (6.21), with 324 caregivers (85.3%) reporting total objective burden and 310 (84.2%) reporting subjective burden. FBIS scores were positively associated with PANSS scores but negatively with GAF P<0.001, respectively. Mean FBIS reduced with medication compliance categories A and B, P<0.01, respectively, but increased in category F, P<0.001. In all, 51.1% scored >/=3 on GHQ. CONCLUSION: Caregivers of schizophrenia patients experience enormous burden and are at risk for mental disorders. The severity of this burden is related to the level of psychopathology and medication adeherence, thereby adding to the available evidence pointing to the need for clinicians to optimize patients' management to prevent psychological distress in carers of such patients. FAU - Lasebikan, V O AU - Lasebikan VO AD - Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria. FAU - Ayinde, O O AU - Ayinde OO LA - eng PT - Journal Article PL - United States TA - Indian J Psychol Med JT - Indian journal of psychological medicine JID - 7910727 PMC - PMC3775044 OTO - NOTNLM OT - Anti-psychotic medication OT - Yoruba version of family burden interview schedule OT - caregiver's burden OT - psychopathology OT - schizophrenia COIS- Conflict of Interest: None. EDAT- 2013/09/21 06:00 MHDA- 2013/09/21 06:01 PMCR- 2013/04/01 CRDT- 2013/09/20 06:00 PHST- 2013/09/20 06:00 [entrez] PHST- 2013/09/21 06:00 [pubmed] PHST- 2013/09/21 06:01 [medline] PHST- 2013/04/01 00:00 [pmc-release] AID - IJPsyM-35-135 [pii] AID - 10.4103/0253-7176.116237 [doi] PST - ppublish SO - Indian J Psychol Med. 2013 Apr;35(2):135-40. doi: 10.4103/0253-7176.116237.