PMID- 24053673
OWN - NLM
STAT- MEDLINE
DCOM- 20140512
LR  - 20131023
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 30
IP  - 11
DP  - 2013
TI  - Multivariate optimisation of an ultrasound assisted-matrix solid-phase dispersion 
      method combined with LC-fluorescence detection for simultaneous extraction and 
      determination of aflatoxins in pistachio nut samples.
PG  - 1954-62
LID - 10.1080/19440049.2013.832401 [doi]
AB  - This paper describes the application of ultrasound-assisted matrix solid-phase 
      dispersion as an extraction and clean-up procedure for aflatoxins (B1, B2, G1 and 
      G2) and subsequent determination by LC-fluorescence detection. A Box-Behnken 
      design was used to determine the parameters influencing the extraction procedure 
      through response surface methodology and experimental design. The influence of 
      different variables including type of dispersing phase, sample-to-dispersing 
      phase ratio, type and quantity of clean-up phase, ultrasonication time, 
      ultrasonication temperature, nature and volume of the elution solvent were 
      investigated in the optimisation study. C18, graphitic carbon black and 
      acetonitrile were selected as dispersing phase, clean-up phase and elution 
      solvent, respectively. The optimised values were sample-to-dispersing phase ratio 
      of 1:1, 50 mg of graphitic carbon black, 11 min ultrasonication time, 30 degrees C 
      ultrasonication temperature and 3 ml acetonitrile. Under the optimal conditions 
      the limits of detection (LODs) were ranged from 0.04-0.11 microg kg(-1) and the 
      relative standard deviations (RSDs) of the extraction method were less than 8.6%. 
      The recoveries of the matrix solid-phase dispersion process ranged from 74% to 
      78% with relative standard deviation lower than 9% in all cases. Finally, the 
      matrix solid-phase dispersion was successfully applied to extraction of trace 
      amounts of aflatoxins in pistachio samples.
FAU - Manoochehri, Mahboobeh
AU  - Manoochehri M
AD  - a Department of Chemistry, Central Tehran Branch , Islamic Azad University , 
      Tehran , Iran.
FAU - Asgharinezhad, Ali Akbar
AU  - Asgharinezhad AA
FAU - Safaei, Mahdi
AU  - Safaei M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130923
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Aflatoxins)
RN  - 0 (Magnesium Silicates)
RN  - 1343-88-0 (Florisil)
SB  - IM
MH  - Aflatoxins/*analysis
MH  - Analysis of Variance
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Fluorometry
MH  - Food Analysis/*methods
MH  - Food Contamination/analysis
MH  - Magnesium Silicates
MH  - Nuts/*chemistry
MH  - Pistacia/*chemistry
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/*methods
MH  - Ultrasonics
EDAT- 2013/09/24 06:00
MHDA- 2014/05/13 06:00
CRDT- 2013/09/24 06:00
PHST- 2013/09/24 06:00 [entrez]
PHST- 2013/09/24 06:00 [pubmed]
PHST- 2014/05/13 06:00 [medline]
AID - 10.1080/19440049.2013.832401 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(11):1954-62. 
      doi: 10.1080/19440049.2013.832401. Epub 2013 Sep 23.