PMID- 24054273
OWN - NLM
STAT- MEDLINE
DCOM- 20140220
LR  - 20191210
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 143
DP  - 2014 Jan 15
TI  - Determination of volatile components of saffron by optimised ultrasound-assisted 
      extraction in tandem with dispersive liquid-liquid microextraction followed by 
      gas chromatography-mass spectrometry.
PG  - 499-505
LID - S0308-8146(13)01093-5 [pii]
LID - 10.1016/j.foodchem.2013.08.024 [doi]
AB  - In the present research, a combined extraction method of ultrasound-assisted 
      extraction (UAE) in conjunction with dispersive liquid-liquid microextraction 
      (DLLME) was applied to isolation and enrichment of saffron volatiles. The 
      extracted components of the saffron were separated and determined by gas 
      chromatography-mass spectrometry (GC-MS) technique. The mixture of 
      methanol/acetonitrile was chosen for the extraction of the compounds and 
      chloroform was used at the preconcentration stage. The important parameters, such 
      as composition of extraction solvent, volume of preconcentration solvent, 
      ultrasonic applying time, and salt concentration were optimised by using a 
      half-fraction factorial central composite design (CCD). Under the optimal 
      conditions, the linear dynamic ranges (LDRs) were 10-10,000mgL(-)(1). The 
      determination coefficients (R(2)) were from 0.9990 to 0.9997. The limits of 
      detection (LODs) and limits of quantification (LOQs) for the extracted compounds 
      were 6-123mgL(-)(1) and 20-406mgL(-)(1), respectively. The relative standard 
      deviations (RSDs) were 2.48-9.82% (n=3). The enhancement factors (EFs) were 
      3.6-41.3.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Sereshti, Hassan
AU  - Sereshti H
AD  - Department of Chemistry, Faculty of Science, University of Tehran, P.O. Box 
      14155-64555, Tehran, Iran. Electronic address: sereshti@khayam.ut.ac.ir.
FAU - Heidari, Reza
AU  - Heidari R
FAU - Samadi, Soheila
AU  - Samadi S
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20130813
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Plant Extracts)
RN  - 0 (Volatile Organic Compounds)
SB  - IM
MH  - Crocus/*chemistry
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Liquid Phase Microextraction/*methods
MH  - Molecular Structure
MH  - Plant Extracts/*chemistry/*isolation & purification
MH  - Ultrasonics/*methods
MH  - Volatile Organic Compounds/*chemistry/*isolation & purification
OTO - NOTNLM
OT  - Central composite design
OT  - Dispersive liquid-liquid microextraction
OT  - Gas chromatography-mass spectrometry
OT  - Saffron
OT  - Ultrasonic-assisted extraction
EDAT- 2013/09/24 06:00
MHDA- 2014/02/22 06:00
CRDT- 2013/09/24 06:00
PHST- 2012/11/23 00:00 [received]
PHST- 2013/08/02 00:00 [revised]
PHST- 2013/08/06 00:00 [accepted]
PHST- 2013/09/24 06:00 [entrez]
PHST- 2013/09/24 06:00 [pubmed]
PHST- 2014/02/22 06:00 [medline]
AID - S0308-8146(13)01093-5 [pii]
AID - 10.1016/j.foodchem.2013.08.024 [doi]
PST - ppublish
SO  - Food Chem. 2014 Jan 15;143:499-505. doi: 10.1016/j.foodchem.2013.08.024. Epub 
      2013 Aug 13.