PMID- 24055176
OWN - NLM
STAT- MEDLINE
DCOM- 20160222
LR  - 20221207
IS  - 1579-2021 (Electronic)
IS  - 1575-0922 (Linking)
VI  - 61
IP  - 1
DP  - 2014 Jan
TI  - Quality of life and satisfaction with treatment in subjects with type 2 diabetes: 
      results in Spain of the PANORAMA study.
PG  - 18-26
LID - S1575-0922(13)00207-6 [pii]
LID - 10.1016/j.endonu.2013.05.005 [doi]
AB  - OBJECTIVES: Few studies are available on quality of life and treatment 
      satisfaction of patients with type 2 diabetes mellitus (T2DM). Both of them were 
      the primary objectives of the PANORAMA (NCT00916513) study. Metabolic control, 
      treatment patterns, and management by healthcare professionals were also 
      evaluated. MATERIAL AND METHODS: This multicenter, cross-sectional, observational 
      study randomly recruited>40 year-old patients with T2DM from Spanish healthcare 
      centers. HbA1c was measured using the same technique in all patients, who also 
      completed quality of life (EQ-5D and ADDQoL) and treatment satisfaction (DTSQ) 
      questionnaires and the Hypoglycemia Fear Survey (HFS-II). RESULTS: Fifty-four 
      investigators recruited 751 patients, 60.3% of whom had HbA1c levels <7%. 
      Approximately 25% of patients on monotherapy had HbA1c values >/= 7%, Patients with 
      longer disease duration and more complex treatments, especially with insulin, 
      showed the poorer control. Despite good overall treatment satisfaction (mean 
      29.3+/-6.1, 0 to 36-point scale), patients with a poorer metabolic control, 
      previous hypoglycemia episodes, and more complex therapies had a worse QoL and a 
      greater fear of suffering hypoglycemia. CONCLUSIONS: Despite advances in 
      metabolic control, there are still areas to improve. Early addition of safe drugs 
      to monotherapy would help achieve control objectives without increasing the risk 
      of hypoglycemia, and delaying the start of insulin therapy. This would also 
      improve QoL and treatment satisfaction.
CI  - Copyright (c) 2013 SEEN. Published by Elsevier Espana. All rights reserved.
FAU - Depablos-Velasco, Pedro
AU  - Depablos-Velasco P
AD  - Departamento de Endocrinologia y Metabolismo, Hospital Dr. Negrin, Universidad de 
      Las Palmas, Las Palmas de Gran Canaria, Espana.
FAU - Salguero-Chaves, Emilio
AU  - Salguero-Chaves E
AD  - Servicio Extremeno de Salud, Centro de Atencion primaria de Valdepasillas, 
      Badajoz, Espana.
FAU - Mata-Poyo, Julio
AU  - Mata-Poyo J
AD  - Servicio Extremeno de Salud, Centro de Atencion primaria de Tabara, Zamora, 
      Espana.
FAU - Derivas-Otero, Beatriz
AU  - Derivas-Otero B
AD  - Departamento Medico, AstraZeneca Farmaceutica Spain, S.A., Madrid, Espana.
FAU - Garcia-Sanchez, Ricardo
AU  - Garcia-Sanchez R
AD  - Departamento Medico, Bristol-Myers Squibb, Madrid, Espana.
FAU - Viguera-Ester, Pablo
AU  - Viguera-Ester P
AD  - Departamento Medico, AstraZeneca Farmaceutica Spain, S.A., Madrid, Espana. 
      Electronic address: Pablo.viguera@astrazeneca.com.
LA  - eng
LA  - spa
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20130919
PL  - Spain
TA  - Endocrinol Nutr
JT  - Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y 
      Nutricion
JID - 100886482
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Combined Modality Therapy
MH  - Cross-Sectional Studies
MH  - Diabetes Complications/epidemiology/psychology
MH  - Diabetes Mellitus, Type 2/blood/epidemiology/*psychology/therapy
MH  - Diet, Diabetic/psychology
MH  - Europe
MH  - Exercise Therapy/psychology
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Hypoglycemia/chemically induced/etiology/psychology
MH  - Hypoglycemic Agents/adverse effects/therapeutic use
MH  - Insulin/adverse effects/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Motor Activity
MH  - Patient Compliance
MH  - *Patient Satisfaction
MH  - *Quality of Life
MH  - Risk
MH  - Spain/epidemiology
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Calidad de vida
OT  - Diabetes mellitus tipo 2
OT  - Quality of life
OT  - Satisfaccion con el tratamiento
OT  - Treatment satisfaction
OT  - Type 2 diabetes mellitus
EDAT- 2013/09/24 06:00
MHDA- 2016/02/24 06:00
CRDT- 2013/09/24 06:00
PHST- 2013/04/03 00:00 [received]
PHST- 2013/05/09 00:00 [revised]
PHST- 2013/05/27 00:00 [accepted]
PHST- 2013/09/24 06:00 [entrez]
PHST- 2013/09/24 06:00 [pubmed]
PHST- 2016/02/24 06:00 [medline]
AID - S1575-0922(13)00207-6 [pii]
AID - 10.1016/j.endonu.2013.05.005 [doi]
PST - ppublish
SO  - Endocrinol Nutr. 2014 Jan;61(1):18-26. doi: 10.1016/j.endonu.2013.05.005. Epub 
      2013 Sep 19.