PMID- 24057543
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130924
LR  - 20211021
IS  - 0179-0358 (Print)
IS  - 0179-0358 (Linking)
VI  - 11
IP  - 2-3
DP  - 1996 Mar
TI  - Totally implantable vascular access devices in 131 pediatric oncology patients.
PG  - 156-8
LID - 10.1007/BF00183752 [doi]
AB  - The use of totally implantable vascular access devices (TIVAD) has gained 
      acceptance in oncology patients, with lower overall complications and maintenance 
      costs than percutaneous silastic catheters. We inserted 135 TIVAD in 131 selected 
      pediatric oncology patients (mean age 8.9 years) for chemotherapy of 68 solid 
      tumors, 39 leukemias, and 24 lymphomas. Patients were required to have an 
      absolute neutrophil count of 1,000/mul prior to TIVAD insertion. The cumulative 
      duration of access was 45,098 days, with a mean of 334 days per device (range 5 
      to 981 days). At the time of review, 53 (39%) TIVAD were functioning without 
      complication, 69 (51%) were removed at the end of therapy or were functioning at 
      the time of death, and 13 (9.6%) were removed due to complications. Complications 
      (n = 23) included 12 episodes of septicemia and 4 pocket infections for an 
      infection rate of 11.8% (1 in 2,819 access days). Infections were more common in 
      patients with leukemia compared to all others (P <0.001). Coagulase-negative 
      staphylococci were isolated in 10 of the 16 infections; 7 infections resolved 
      with antibiotic therapy. Mechanical complications were associated with 7 (5.2%) 
      devices (1 in 6,443 access days). These data suggest that in selected 
      non-neutropenic pediatric oncology patients, TIVAD can be utilized with minimal 
      morbidity in the delivery of long-term chemotherapy.
FAU - Sola, J E
AU  - Sola JE
AD  - Division of Pediatric Surgery, Department of Surgery, The Johns Hopkins 
      University School of Medicine, 600 N. Wolfe Street, CMSC 7-113, 21287-3716, 
      Baltimore, MA, USA.
FAU - Stone, M M
AU  - Stone MM
FAU - Colombani, P M
AU  - Colombani PM
LA  - eng
PT  - Journal Article
DEP - 20130921
PL  - Germany
TA  - Pediatr Surg Int
JT  - Pediatric surgery international
JID - 8609169
EDAT- 1996/03/01 00:00
MHDA- 1996/03/01 00:01
CRDT- 2013/09/24 06:00
PHST- 1995/04/25 00:00 [accepted]
PHST- 2013/09/24 06:00 [entrez]
PHST- 1996/03/01 00:00 [pubmed]
PHST- 1996/03/01 00:01 [medline]
AID - 10.1007/BF00183752 [doi]
PST - ppublish
SO  - Pediatr Surg Int. 1996 Mar;11(2-3):156-8. doi: 10.1007/BF00183752. Epub 2013 Sep 
      21.