PMID- 24067406 OWN - NLM STAT- MEDLINE DCOM- 20140819 LR - 20220716 IS - 1469-4409 (Electronic) IS - 0950-2688 (Print) IS - 0950-2688 (Linking) VI - 142 IP - 7 DP - 2014 Jul TI - Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA. PG - 1459-66 LID - 10.1017/S0950268813002355 [doi] AB - The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration. FAU - Campo, M AU - Campo M AD - Department of Pulmonary and Critical Care Medicine,University of Washington,WA,USA. FAU - Shrestha, A AU - Shrestha A AD - Department of Epidemiology,University of Washington,WA,USA. FAU - Oren, E AU - Oren E AD - Department of Epidemiology,University of Washington,WA,USA. FAU - Thiede, H AU - Thiede H AD - Department of Epidemiology,University of Washington,WA,USA. FAU - Duchin, J AU - Duchin J AD - Department of Epidemiology,University of Washington,WA,USA. FAU - Narita, M AU - Narita M AD - Department of Pulmonary and Critical Care Medicine,University of Washington,WA,USA. FAU - Crothers, K AU - Crothers K AD - Department of Pulmonary and Critical Care Medicine,University of Washington,WA,USA. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130925 PL - England TA - Epidemiol Infect JT - Epidemiology and infection JID - 8703737 RN - 0 (Antitubercular Agents) SB - IM MH - Adult MH - Antitubercular Agents/adverse effects/therapeutic use MH - Coinfection/*epidemiology/microbiology/virology MH - Female MH - Hepatitis C/*epidemiology/*microbiology MH - Humans MH - Male MH - Middle Aged MH - Retrospective Studies MH - Risk Factors MH - Treatment Outcome MH - Tuberculosis/drug therapy/*epidemiology/*virology MH - Washington/epidemiology PMC - PMC9151201 EDAT- 2013/09/27 06:00 MHDA- 2014/08/20 06:00 PMCR- 2022/05/31 CRDT- 2013/09/27 06:00 PHST- 2013/09/27 06:00 [entrez] PHST- 2013/09/27 06:00 [pubmed] PHST- 2014/08/20 06:00 [medline] PHST- 2022/05/31 00:00 [pmc-release] AID - S0950268813002355 [pii] AID - 00235 [pii] AID - 10.1017/S0950268813002355 [doi] PST - ppublish SO - Epidemiol Infect. 2014 Jul;142(7):1459-66. doi: 10.1017/S0950268813002355. Epub 2013 Sep 25.