PMID- 24070909 OWN - NLM STAT- MEDLINE DCOM- 20140605 LR - 20151119 IS - 1879-1379 (Electronic) IS - 0022-3956 (Linking) VI - 47 IP - 12 DP - 2013 Dec TI - On the quest for a biomechanism of transsexualism: is there a role for BDNF? PG - 2015-7 LID - S0022-3956(13)00274-4 [pii] LID - 10.1016/j.jpsychires.2013.08.023 [doi] AB - Previous studies hypothesized a neurobiological mechanism for gender identity disorder (GID). Recently a possible role for serum brain-derived neurotrophic factor (BDNF) was suggested on the basis of reduced serum BDNF levels in male-to-female individuals. Here we review the question whether there is indeed a role of BDNF in the development of transsexualism. CI - Copyright (c) 2013 Elsevier Ltd. All rights reserved. FAU - Fuss, Johannes AU - Fuss J AD - Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J 5, 68159 Mannheim, Germany. Electronic address: johannes.fuss@zi-mannheim.de. FAU - Biedermann, Sarah V AU - Biedermann SV FAU - Stalla, Gunter K AU - Stalla GK FAU - Auer, Matthias K AU - Auer MK LA - eng PT - Letter PT - Review DEP - 20130907 PL - England TA - J Psychiatr Res JT - Journal of psychiatric research JID - 0376331 RN - 0 (Biomarkers) RN - 0 (Brain-Derived Neurotrophic Factor) SB - IM CIN - J Psychiatr Res. 2014 Mar;50:16-7. PMID: 24332481 MH - Biomarkers/blood MH - Body Mass Index MH - Brain-Derived Neurotrophic Factor/*blood MH - Female MH - *Gender Identity MH - Humans MH - Male MH - Transsexualism/*blood OTO - NOTNLM OT - Gender identity disorder OT - Male to female OT - Neurobiology OT - Neuroplasticity OT - Transgender OT - Transsexual EDAT- 2013/09/28 06:00 MHDA- 2014/06/06 06:00 CRDT- 2013/09/28 06:00 PHST- 2013/06/05 00:00 [received] PHST- 2013/08/29 00:00 [revised] PHST- 2013/08/29 00:00 [accepted] PHST- 2013/09/28 06:00 [entrez] PHST- 2013/09/28 06:00 [pubmed] PHST- 2014/06/06 06:00 [medline] AID - S0022-3956(13)00274-4 [pii] AID - 10.1016/j.jpsychires.2013.08.023 [doi] PST - ppublish SO - J Psychiatr Res. 2013 Dec;47(12):2015-7. doi: 10.1016/j.jpsychires.2013.08.023. Epub 2013 Sep 7.