PMID- 24081640
OWN - NLM
STAT- MEDLINE
DCOM- 20161007
LR  - 20161230
IS  - 1477-0393 (Electronic)
IS  - 0748-2337 (Linking)
VI  - 32
IP  - 1
DP  - 2016 Jan
TI  - Comparative toxicity of Paraquat herbicide and some plant extracts in Lymnaea 
      natalensis snails.
PG  - 143-53
LID - 10.1177/0748233713498457 [doi]
AB  - Paraquat has been shown to be a highly toxic compound for humans and animals, and 
      many cases of acute poisoning and death have been reported over the past few 
      decades. The present study was undertaken to evaluate comprehensively herbicides 
      (Paraquat) and some plant extracts to biochemical aspects of Lymnaea natalensis 
      snails. It was found that the exposure of L. natalensis to Paraquat and plant 
      extracts led to a significant reduction in the infectivity of Fasciola gigantica 
      miracidia to the snail. The glucose level in hemolymph of exposed snails was 
      elevated, while the glycogen showed a decrease in soft tissues when compared with 
      the control group. In addition, the activity level of some enzymes representing 
      glycolytic enzymes as hexokinase (HK), pyruvate kinase (PK), phosphofructokinase 
      (PFK), lactate dehydrogenase (LDH), and glucose phosphate isomerase (GPI) in 
      snail's tissues were reduced in response to the treatment. It was concluded that 
      the pollution of the aquatic environment by herbicide would adversely affect the 
      metabolism of the L. natalensis snails. Snails treated with Agave attenuate, Ammi 
      visnaga, and Canna iridiflora plant had less toxic effect compared to snails 
      treated with Paraquat.
CI  - (c) The Author(s) 2013.
FAU - Bakry, Fayez A
AU  - Bakry FA
AD  - Medical Malacology Department, Theodor Bilharz Research Institute, Giza, Egypt 
      fayezbakery@yahoo.com.
FAU - Eleiwa, Mona E
AU  - Eleiwa ME
AD  - Department of Botany, Cairo University, Cairo, Egypt.
FAU - Taha, Samir A
AU  - Taha SA
AD  - Department of Zoology, Zagazig University, Zagazig, Egypt.
FAU - Ismil, Somya M
AU  - Ismil SM
AD  - Department of Zoology, Cairo University, Cairo, Egypt.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20130930
PL  - England
TA  - Toxicol Ind Health
JT  - Toxicology and industrial health
JID - 8602702
RN  - 0 (Herbicides)
RN  - 0 (Phytochemicals)
RN  - 0 (Plant Extracts)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.7.1 - (Phosphofructokinases)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.1.40 (Pyruvate Kinase)
RN  - EC 5.3.1.9 (Glucose-6-Phosphate Isomerase)
RN  - PLG39H7695 (Paraquat)
SB  - IM
MH  - Animals
MH  - Fasciola/growth & development
MH  - Glucose-6-Phosphate Isomerase/metabolism
MH  - Herbicides/*toxicity
MH  - Hexokinase/metabolism
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Lethal Dose 50
MH  - Lymnaea/*drug effects/metabolism/parasitology
MH  - Paraquat/*toxicity
MH  - Phosphofructokinases/metabolism
MH  - Phytochemicals/toxicity
MH  - Plant Extracts/*toxicity
MH  - Pyruvate Kinase/metabolism
OTO - NOTNLM
OT  - Agave attenuate
OT  - Ammi visnaga
OT  - Canna iridiflora plant
OT  - Fasciola gigantica miracidia
OT  - Lymnaea natalensis snails
OT  - Paraquat herbicide
EDAT- 2013/10/02 06:00
MHDA- 2016/10/08 06:00
CRDT- 2013/10/02 06:00
PHST- 2013/10/02 06:00 [entrez]
PHST- 2013/10/02 06:00 [pubmed]
PHST- 2016/10/08 06:00 [medline]
AID - 0748233713498457 [pii]
AID - 10.1177/0748233713498457 [doi]
PST - ppublish
SO  - Toxicol Ind Health. 2016 Jan;32(1):143-53. doi: 10.1177/0748233713498457. Epub 
      2013 Sep 30.