PMID- 24088856
OWN - NLM
STAT- MEDLINE
DCOM- 20140623
LR  - 20211021
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Print)
IS  - 0095-1137 (Linking)
VI  - 51
IP  - 12
DP  - 2013 Dec
TI  - Marseillevirus adenitis in an 11-month-old child.
PG  - 4102-5
LID - 10.1128/JCM.01918-13 [doi]
AB  - A Marseillevirus (giant virus of amoeba) has been found in the blood and stool 
      samples of individuals who otherwise appear to be healthy. During an attempt to 
      define a serological cutoff for Marseillevirus by enzyme-linked immunosorbent 
      assay (ELISA) in children, we serendipitously detected high antibody responses to 
      Marseillevirus in an 11-month-old boy suffering from adenitis. Marseillevirus DNA 
      was then found in his blood using PCR and with a unique sequence. We identified 
      Marseillevirus in a lymph node using fluorescence in situ hybridization (FISH) 
      and immunohistochemistry, and the lymph node was removed surgically. The child 
      was declared to be cured 1 year later. We conclude that adenitis during early 
      childhood may be caused by Marseillevirus.
FAU - Popgeorgiev, Nikolay
AU  - Popgeorgiev N
AD  - Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, 
      Faculte de Medecine, CNRS UMR 7278, IRD 198, Aix-Marseille Universite, Marseille, 
      France.
FAU - Michel, Gerard
AU  - Michel G
FAU - Lepidi, Hubert
AU  - Lepidi H
FAU - Raoult, Didier
AU  - Raoult D
FAU - Desnues, Christelle
AU  - Desnues C
LA  - eng
SI  - GENBANK/KC921393
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20131002
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
RN  - 0 (Antibodies, Viral)
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/blood
MH  - DNA Virus Infections/*diagnosis/*virology
MH  - DNA Viruses/*classification/genetics/*isolation & purification
MH  - DNA, Viral/blood/chemistry/genetics
MH  - Humans
MH  - Immunohistochemistry
MH  - In Situ Hybridization, Fluorescence
MH  - Infant
MH  - Lymph Nodes/virology
MH  - Lymphadenitis/*diagnosis/pathology/*virology
MH  - Male
MH  - Microscopy
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - Sequence Analysis, DNA
PMC - PMC3838047
EDAT- 2013/10/04 06:00
MHDA- 2014/06/24 06:00
PMCR- 2014/06/01
CRDT- 2013/10/04 06:00
PHST- 2013/10/04 06:00 [entrez]
PHST- 2013/10/04 06:00 [pubmed]
PHST- 2014/06/24 06:00 [medline]
PHST- 2014/06/01 00:00 [pmc-release]
AID - JCM.01918-13 [pii]
AID - 01918-13 [pii]
AID - 10.1128/JCM.01918-13 [doi]
PST - ppublish
SO  - J Clin Microbiol. 2013 Dec;51(12):4102-5. doi: 10.1128/JCM.01918-13. Epub 2013 
      Oct 2.