PMID- 24099902
OWN - NLM
STAT- MEDLINE
DCOM- 20150126
LR  - 20131119
IS  - 1578-1747 (Electronic)
IS  - 0211-139X (Linking)
VI  - 48
IP  - 6
DP  - 2013 Nov-Dec
TI  - [Proton bomb inhibitors: a study of the prescription in a functional recovery 
      unit].
PG  - 269-71
LID - S0211-139X(13)00140-6 [pii]
LID - 10.1016/j.regg.2013.07.004 [doi]
AB  - INTRODUCTION: The use of proton pump inhibitors (PPI) has increased exponentially 
      since they were introduced. However concerns have been raised regarding the 
      appropriateness of these prescriptions, and the potential side effects, 
      particularly in frail elderly people, as well as the cost of this treatment. The 
      aim of this study was to assess the extent and appropriateness of PPI prescribing 
      in a group of patients over 65 years old admitted to the functional recovery unit 
      of a medium-stay hospital. MATERIALS AND METHODS: A retrospective review of 
      inpatient prescribing of PPI was carried out in a functional recovery unit in 
      Hospital de la Fuenfria, selecting those older than 65 years, who were admitted 
      during 2011. Data obtained from medical records included, prescription of a PPI 
      before admission and at the time of discharge from hospital (both acute care 
      hospital and Hospital de la Fuenfria), type of PPI, and indications for their 
      prescription. RESULTS: Inclusion criteria were met by 296 patients (mean age 78.8 
      years, 70.6% females). A total of 45.3, 79.1 and 75.5% of patients were on PPIs 
      before admission, and at the time of being discharge from acute care hospital, 
      and Hospital de la Fuenfria, respectively. A valid indication for therapy was not 
      apparent in 62.7, 30.8 and 54.2% of them. Omeprazole was the most widely 
      prescribed PPI. CONCLUSIONS: There appears to be a widespread and inappropriate 
      use of PPIs in hospital practice. Interventions are needed to curtail this 
      inappropriate prescribing practice, avoiding side effects and drug interactions.
CI  - Copyright (c) 2013 SEGG. Published by Elsevier Espana. All rights reserved.
FAU - Lopez-Doriga Bonnardeaux, Pedro
AU  - Lopez-Doriga Bonnardeaux P
AD  - Unidad de Recuperacion Funcional, Hospital de la Fuenfria, Cercedilla, Madrid, 
      Espana.
FAU - Neira Alvarez, Marta
AU  - Neira Alvarez M
FAU - Mansilla Laguia, Sara
AU  - Mansilla Laguia S
LA  - spa
PT  - English Abstract
PT  - Journal Article
PT  - Observational Study
TT  - Inhibidores de la bomba de protones: estudio de prescripcion en una Unidad de 
      Recuperacion Funcional.
DEP - 20131005
PL  - Spain
TA  - Rev Esp Geriatr Gerontol
JT  - Revista espanola de geriatria y gerontologia
JID - 8009022
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Hospital Units
MH  - Humans
MH  - Inappropriate Prescribing/*statistics & numerical data
MH  - Male
MH  - Proton Pump Inhibitors/*therapeutic use
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Antiinflamatorios no esteroideos
OT  - Gastroesophageal reflux
OT  - Inappropriate prescribing
OT  - Inhibidores de la bomba de protones
OT  - Non-steroidal anti-inflammatory agents
OT  - Prescripcion inapropiada
OT  - Proton pump inhibitors
OT  - Reflujo gastroesofagico
EDAT- 2013/10/09 06:00
MHDA- 2015/01/27 06:00
CRDT- 2013/10/09 06:00
PHST- 2013/03/17 00:00 [received]
PHST- 2013/07/18 00:00 [revised]
PHST- 2013/07/22 00:00 [accepted]
PHST- 2013/10/09 06:00 [entrez]
PHST- 2013/10/09 06:00 [pubmed]
PHST- 2015/01/27 06:00 [medline]
AID - S0211-139X(13)00140-6 [pii]
AID - 10.1016/j.regg.2013.07.004 [doi]
PST - ppublish
SO  - Rev Esp Geriatr Gerontol. 2013 Nov-Dec;48(6):269-71. doi: 
      10.1016/j.regg.2013.07.004. Epub 2013 Oct 5.