PMID- 24101446
OWN - NLM
STAT- MEDLINE
DCOM- 20140812
LR  - 20240213
IS  - 1873-4626 (Electronic)
IS  - 1091-255X (Linking)
VI  - 17
IP  - 12
DP  - 2013 Dec
TI  - Enucleation of pancreatic lesions: indications, outcomes, and risk factors for 
      clinical pancreatic fistula.
PG  - 2099-104
LID - 10.1007/s11605-013-2355-6 [doi]
AB  - BACKGROUND: There are few large samples and single-center series that focus on 
      the outcomes of pancreatic enucleation and risk factors for clinical pancreatic 
      fistula (PF). This study aimed to evaluate the indications, short- and long-term 
      results, and risk factors for clinical PF after pancreatic enucleation. METHODS: 
      Patients who underwent pancreatic enucleation from January 2005 to April 2011 at 
      the Peking Union Medical College Hospital in China were included. Clinical data 
      were collected and analyzed. RESULTS: A total of 119 patients underwent 
      enucleation. PF was the most common complication; the incidence of clinical PF 
      (grades B and C) was 27.7 %. The most common indications were endocrine neoplasms 
      (76.5 %). During a median follow-up of 41 months, no patient developed exocrine 
      insufficiency. Three elderly patients developed non-insulin-dependent diabetes 
      mellitus. One patient with VIPoma developed recurrence and liver metastasis. New 
      York Heart Association (NYHA) class II or III (P = 0.009; hazard ratio (HR) 
      3.191; 95 % confidence interval (CI) 1.334-7.632), operative time >/=180 min 
      (P = 0.025; HR 2.664; 95 % CI 1.112-6.386) were the independent risk factors for 
      clinical PF. CONCLUSION: Enucleation is a safe and effective treatment for benign 
      and low malignant lesions of the pancreas. NYHA class II or III and operation 
      time of >/=180 min are independent risk factors for clinical PF.
FAU - Zhang, Taiping
AU  - Zhang T
AD  - Department of General Surgery, Peking Union Medical College Hospital, Chinese 
      Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, 
      Wangfujing Street, Beijing, 100730, China.
FAU - Xu, Jianwei
AU  - Xu J
FAU - Wang, Tianxiao
AU  - Wang T
FAU - Liao, Quan
AU  - Liao Q
FAU - Dai, Menghua
AU  - Dai M
FAU - Zhao, Yupei
AU  - Zhao Y
LA  - eng
PT  - Journal Article
DEP - 20131008
PL  - Netherlands
TA  - J Gastrointest Surg
JT  - Journal of gastrointestinal surgery : official journal of the Society for Surgery 
      of the Alimentary Tract
JID - 9706084
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Digestive System Surgical Procedures/adverse effects/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Pancreatic Diseases/*surgery
MH  - Pancreatic Fistula/epidemiology/*surgery
MH  - Pancreatic Neoplasms/*surgery
MH  - Postoperative Complications/epidemiology
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2013/10/09 06:00
MHDA- 2014/08/13 06:00
CRDT- 2013/10/09 06:00
PHST- 2013/04/24 00:00 [received]
PHST- 2013/09/05 00:00 [accepted]
PHST- 2013/10/09 06:00 [entrez]
PHST- 2013/10/09 06:00 [pubmed]
PHST- 2014/08/13 06:00 [medline]
AID - S1091-255X(23)04049-0 [pii]
AID - 10.1007/s11605-013-2355-6 [doi]
PST - ppublish
SO  - J Gastrointest Surg. 2013 Dec;17(12):2099-104. doi: 10.1007/s11605-013-2355-6. 
      Epub 2013 Oct 8.