PMID- 24107128 OWN - NLM STAT- MEDLINE DCOM- 20150416 LR - 20140617 IS - 1476-4954 (Electronic) IS - 1476-4954 (Linking) VI - 27 IP - 11 DP - 2014 Jul TI - Effect of mode of delivery on macronutrient content of breast milk. PG - 1099-102 LID - 10.3109/14767058.2013.850486 [doi] AB - OBJECTIVE: To determine the effect of delivery type on macronutrient content of colostral milk. MATERIALS AND METHODS: The study was conducted at Zekai Tahir Burak Maternity Teaching Hospital. Colostral milk samples from term lactating mothers who gave birth by vaginal or cesarean delivery (CD) were obtained on the 2nd postpartum day. Milk protein, fat, carbohydrate (CHO) and energy levels were measured by using a mid-infrared human milk analyzer. RESULTS: A total of 204 term lactating mothers were recruited to the study; 111 mothers gave birth by vaginal route and 93 mothers by CD. Protein levels were statistically lower in colostral milk of mothers after CD compared to mothers who delivered vaginally (median 2.4 (range 0.3-6.4) g/dl versus 3 (0.5-6.3) g/dl, respectively; p = 0.036). Colostral fat, CHO and energy levels were similar between groups. In linear regression analysis, CD and maternal age were independently associated with lower protein content in colostrum. CONCLUSION: Vaginal delivery is associated with higher colostrum protein content. Hormonal activity induced by labor pain and uterine contractions might account for the alterations in the protein composition of human milk to facilitate optimal development of important physiologic functions in newborns. FAU - Dizdar, Evrim Alyamac AU - Dizdar EA AD - Neonatal Intensive Care Unit, Zekai Tahir Burak Maternity Teaching Hospital , Ankara , Turkey and. FAU - Sari, Fatma Nur AU - Sari FN FAU - Degirmencioglu, Halil AU - Degirmencioglu H FAU - Canpolat, Fuat Emre AU - Canpolat FE FAU - Oguz, Serife Suna AU - Oguz SS FAU - Uras, Nurdan AU - Uras N FAU - Dilmen, Ugur AU - Dilmen U LA - eng PT - Journal Article DEP - 20131024 PL - England TA - J Matern Fetal Neonatal Med JT - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JID - 101136916 RN - 0 (Carbohydrates) RN - 0 (Lipids) RN - 0 (Milk Proteins) SB - IM MH - Adolescent MH - Adult MH - Carbohydrates/*analysis MH - Colostrum/chemistry MH - Delivery, Obstetric/*methods/statistics & numerical data MH - Female MH - Humans MH - Infant, Newborn MH - Lactation/metabolism MH - Lipids/*analysis MH - Milk Proteins/*analysis/metabolism MH - Milk, Human/*chemistry/metabolism MH - Pregnancy MH - Young Adult OTO - NOTNLM OT - Breast milk OT - colostrum OT - delivery mode OT - milk composition EDAT- 2013/10/11 06:00 MHDA- 2015/04/17 06:00 CRDT- 2013/10/11 06:00 PHST- 2013/10/11 06:00 [entrez] PHST- 2013/10/11 06:00 [pubmed] PHST- 2015/04/17 06:00 [medline] AID - 10.3109/14767058.2013.850486 [doi] PST - ppublish SO - J Matern Fetal Neonatal Med. 2014 Jul;27(11):1099-102. doi: 10.3109/14767058.2013.850486. Epub 2013 Oct 24.