PMID- 24110632
OWN - NLM
STAT- MEDLINE
DCOM- 20150714
LR  - 20200928
IS  - 2694-0604 (Electronic)
IS  - 2375-7477 (Linking)
VI  - 2013
DP  - 2013
TI  - Computational simulation to understand vision changes during prolonged 
      weightlessness.
PG  - 4094-7
LID - 10.1109/EMBC.2013.6610445 [doi]
AB  - A mathematical model of whole body and cerebral hemodynamics is a useful tool for 
      investigating visual impairment and intracranial pressure (VIIP), a recently 
      described condition associated with space flight. VIIP involves loss of visual 
      acuity, anatomical changes to the eye, and, usually, elevated cerebrospinal fluid 
      pressure. Loss of visual acuity is a significant threat to astronaut health and 
      performance. It is therefore important to understand the pathogenesis of VIIP. 
      Some of the experimental measurements that could lead to better understanding of 
      the pathophysiology are impossible or infeasible on orbit. A computational 
      implementation of a mathematical model of hypothetical pathophysiological 
      processes is therefore valuable. Such a model is developed, and is used to 
      investigate how changes in vascular compliance or pressure can influence 
      intraocular or intracranial pressure.
FAU - Rose, William C
AU  - Rose WC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Annu Int Conf IEEE Eng Med Biol Soc
JT  - Annual International Conference of the IEEE Engineering in Medicine and Biology 
      Society. IEEE Engineering in Medicine and Biology Society. Annual International 
      Conference
JID - 101763872
SB  - IM
MH  - *Computer Simulation
MH  - Humans
MH  - Intracranial Pressure/physiology
MH  - Kidney/blood supply
MH  - Models, Cardiovascular
MH  - Vision, Ocular/*physiology
MH  - *Weightlessness
EDAT- 2013/10/11 06:00
MHDA- 2015/07/15 06:00
CRDT- 2013/10/11 06:00
PHST- 2013/10/11 06:00 [entrez]
PHST- 2013/10/11 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.1109/EMBC.2013.6610445 [doi]
PST - ppublish
SO  - Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:4094-7. doi: 
      10.1109/EMBC.2013.6610445.