PMID- 24112810
OWN - NLM
STAT- MEDLINE
DCOM- 20141208
LR  - 20140515
IS  - 1365-277X (Electronic)
IS  - 0952-3871 (Linking)
VI  - 27
IP  - 3
DP  - 2014 Jun
TI  - Comparing the effects of meal replacements with an isocaloric reduced-fat diet on 
      nutrient intake and lower urinary tract symptoms in obese men.
PG  - 219-26
LID - 10.1111/jhn.12151 [doi]
AB  - BACKGROUND: Lower urinary tract symptoms (LUTS) in men are associated with 
      obesity, particularly central obesity as measured by waist circumference (WC), 
      and may improve with weight loss. We aimed to compare effects of a 
      meal-replacement based diet with isocaloric reduced-fat plan on LUTS and nutrient 
      intake in obese Asian men. METHODS: Obese Asian [mean (range) body mass index of 
      32.9 (30.5-42.3) kg m(-2) ] men [mean (range) age 40.2 (30-61) years] were 
      randomised to a reduced-fat (< 30% of energy) diet [conventional reduced-fat diet 
      (CD) group; n = 23] or meal-replacement-based plan [meal replacement (MR) group; 
      n = 23], to reduce daily intake by 2000 kJ for 12 weeks. RESULTS: CD and MR 
      groups had statistically significant and similar reductions in weight (-2.6 +/- 1.9 
      kg versus -4.2 +/- 3.8 kg), overall LUTS severity measured with International 
      Prostate Symptom Scale (IPSS) scores (-1.71 +/- 1.93 points versus -2.42 +/- 2.12 
      points) and insulin resistance [homeostasis model assessment (HOMA) calculated 
      from plasma glucose and insulin]. The MR group had significantly greater 
      decreases in WC (-4.8 +/- 3.3 cm versus -2.5 +/- 2.3 cm), fat mass (-2.47 +/- 3.63 kg 
      versus -1.59 +/- 2.32 kg), fat intake, plasma C-reactive protein, and in storage 
      LUTS score (-1.59 +/- 1.33 points versus -1.00 +/- 0.87 points), which was associated 
      with a decreased fat intake (r = 0.48, P = 0.03). A decrease in overall IPSS 
      score was associated with reductions in weight, WC and HOMA. CONCLUSIONS: Weight 
      loss as a result of CD or MR had similar efficacy in relieving LUTS. MR produced 
      greater reductions in fat intake, adiposity and storage LUTS.
CI  - (c) 2013 The British Dietetic Association Ltd.
FAU - Khoo, J
AU  - Khoo J
AD  - Department of Endocrinology, Changi General Hospital, Singapore, Singapore.
FAU - Ling, P-S
AU  - Ling PS
FAU - Chen, R Y-T
AU  - Chen RY
FAU - Ng, K-K
AU  - Ng KK
FAU - Tay, T-L
AU  - Tay TL
FAU - Tan, E
AU  - Tan E
FAU - Cho, L-W
AU  - Cho LW
FAU - Cheong, M
AU  - Cheong M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20130920
PL  - England
TA  - J Hum Nutr Diet
JT  - Journal of human nutrition and dietetics : the official journal of the British 
      Dietetic Association
JID - 8904840
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
SB  - IM
MH  - Adiposity
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Diet
MH  - *Diet, Fat-Restricted
MH  - *Energy Intake
MH  - Energy Metabolism
MH  - Humans
MH  - Insulin/blood
MH  - Insulin Resistance
MH  - Male
MH  - Meals
MH  - Middle Aged
MH  - Obesity/*complications
MH  - Prostatic Diseases/diet therapy
MH  - Urologic Diseases/*diet therapy/*etiology
MH  - Waist Circumference
MH  - Weight Loss
OTO - NOTNLM
OT  - LUTS
OT  - diet
OT  - meal replacements
OT  - obesity
OT  - weight loss
EDAT- 2013/10/12 06:00
MHDA- 2014/12/15 06:00
CRDT- 2013/10/12 06:00
PHST- 2013/10/12 06:00 [entrez]
PHST- 2013/10/12 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - 10.1111/jhn.12151 [doi]
PST - ppublish
SO  - J Hum Nutr Diet. 2014 Jun;27(3):219-26. doi: 10.1111/jhn.12151. Epub 2013 Sep 20.