PMID- 24113000 OWN - NLM STAT- MEDLINE DCOM- 20140806 LR - 20131125 IS - 1096-1208 (Electronic) IS - 0882-4010 (Linking) VI - 65 DP - 2013 Dec TI - Phylogenetic analysis and molecular characteristics of 17 porcine reproductive and respiratory syndrome virus isolates in Southern China from 2010 to 2011. PG - 67-72 LID - S0882-4010(13)00132-0 [pii] LID - 10.1016/j.micpath.2013.09.005 [doi] AB - We analyzed the complete genomic sequences of 17 porcine reproductive and respiratory syndrome virus (PRRSV) isolates from Southern China obtained between 2010 and 2011 and found that four of seven isolates from 2011 were closely related to the JXA1-R strain (vaccine virus of JXA1). This close relationship between field isolates and China domestic vaccine viruses has not been reported to date. The occurrence of vaccine-like viruses potentially creates a threat for the pig breeding industry and brings difficulties for control of this disease. CI - Copyright (c) 2013 Elsevier Ltd. All rights reserved. FAU - Zhang, Minze AU - Zhang M AD - MOA Key Laboratory of Animal Vaccine Development, Ministry of China, College of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Tianhe District, Guangzhou 510642, China. FAU - Xie, Jiexiong AU - Xie J FAU - Sun, Long AU - Sun L FAU - Cao, Zhenpeng AU - Cao Z FAU - Gu, Honglang AU - Gu H FAU - Deng, Shengchao AU - Deng S FAU - Chen, Yao AU - Chen Y FAU - Cao, Zongxi AU - Cao Z FAU - Tang, Fengfeng AU - Tang F FAU - Su, Shuo AU - Su S FAU - Zhang, Guihong AU - Zhang G LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20131007 PL - England TA - Microb Pathog JT - Microbial pathogenesis JID - 8606191 RN - 0 (Vaccines) SB - IM MH - Amino Acid Sequence MH - Animals MH - Base Sequence MH - China/epidemiology MH - Genetic Variation MH - Genome, Viral MH - Genotype MH - Molecular Sequence Data MH - Phylogeny MH - Porcine Reproductive and Respiratory Syndrome/epidemiology/immunology/*virology MH - Porcine respiratory and reproductive syndrome virus/*classification/genetics/isolation & purification MH - Sequence Alignment MH - Sequence Analysis, DNA MH - Swine MH - Vaccines/*genetics OTO - NOTNLM OT - Complete genome OT - GP5 OT - Nsp2 OT - PRRSV EDAT- 2013/10/12 06:00 MHDA- 2014/08/07 06:00 CRDT- 2013/10/12 06:00 PHST- 2013/07/11 00:00 [received] PHST- 2013/09/07 00:00 [revised] PHST- 2013/09/24 00:00 [accepted] PHST- 2013/10/12 06:00 [entrez] PHST- 2013/10/12 06:00 [pubmed] PHST- 2014/08/07 06:00 [medline] AID - S0882-4010(13)00132-0 [pii] AID - 10.1016/j.micpath.2013.09.005 [doi] PST - ppublish SO - Microb Pathog. 2013 Dec;65:67-72. doi: 10.1016/j.micpath.2013.09.005. Epub 2013 Oct 7.