PMID- 24115026
OWN - NLM
STAT- MEDLINE
DCOM- 20140928
LR  - 20131112
IS  - 1521-186X (Electronic)
IS  - 0197-8462 (Linking)
VI  - 34
IP  - 8
DP  - 2013 Dec
TI  - Neurophysiological characterization of transpinal evoked potentials in human leg 
      muscles.
PG  - 630-40
LID - 10.1002/bem.21808 [doi]
AB  - The objectives of this study were to characterize the neurophysiological 
      properties of the compound muscle action potentials (CMAPs) evoked by 
      transcutaneous electric stimulation of the spine (tsESS), and the effects of 
      tsESS on the soleus H-reflex in seated and standing healthy human subjects. In 
      seated semi-prone subjects with the trunk semi-flexed, two re-usable 
      self-adhering electrodes (cathode), connected to act as one electrode, were 
      placed bilaterally on the iliac crests. A re-usable pregelled electrode (anode) 
      was placed on the thoracolumbar region at thoracic 10-lumbar 1 and held under 
      constant pressure throughout the experiment. CMAPs were recorded bilaterally from 
      ankle muscles with subjects seated semi-prone at 1.0, 0.3, 0.2, 0.125, and 0.1 Hz 
      following tsESS. The soleus H-reflex, evoked by posterior tibial nerve 
      stimulation via conventional methods, was measured following tsESS at 
      inter-stimulus intervals (ISIs) that ranged from -100 to 100 ms with the subjects 
      seated semi-prone and during standing. The tsESS-induced CMAPs were not decreased 
      at low stimulation frequencies, and the soleus H-reflex excitability was 
      profoundly decreased by tsESS at ISIs that ranged from -5 to 20 ms with the 
      subjects seated semi-prone and during standing. CMAPs induced by tsESS may be 
      utilized to assess spinal-to-muscle conduction time while bypassing spinal 
      motoneuron excitability and tsESS can be used as a modality to decrease spinal 
      reflex hyper-excitability in neurological disorders.
CI  - (c) 2013 Wiley Periodicals, Inc.
FAU - Knikou, Maria
AU  - Knikou M
AD  - Graduate Center, City University of New York, New York, New York.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130920
PL  - United States
TA  - Bioelectromagnetics
JT  - Bioelectromagnetics
JID - 8008281
SB  - IM
MH  - Adult
MH  - *Electric Stimulation
MH  - *Evoked Potentials
MH  - Female
MH  - Humans
MH  - *Leg
MH  - *Lumbar Vertebrae
MH  - Male
MH  - Muscles/*physiology
MH  - Posture/physiology
MH  - *Thoracic Vertebrae
MH  - Young Adult
OTO - NOTNLM
OT  - electric stimulation
OT  - low-frequency depression
OT  - multisegmental responses
OT  - soleus H-reflex
OT  - spine
OT  - thoracolumbar region
EDAT- 2013/10/12 06:00
MHDA- 2014/10/01 06:00
CRDT- 2013/10/12 06:00
PHST- 2013/04/26 00:00 [received]
PHST- 2013/06/27 00:00 [accepted]
PHST- 2013/10/12 06:00 [entrez]
PHST- 2013/10/12 06:00 [pubmed]
PHST- 2014/10/01 06:00 [medline]
AID - 10.1002/bem.21808 [doi]
PST - ppublish
SO  - Bioelectromagnetics. 2013 Dec;34(8):630-40. doi: 10.1002/bem.21808. Epub 2013 Sep 
      20.