PMID- 24117633
OWN - NLM
STAT- MEDLINE
DCOM- 20131218
LR  - 20180116
IS  - 1749-6632 (Electronic)
IS  - 0077-8923 (Linking)
VI  - 1300
DP  - 2013 Oct
TI  - Respiratory manifestations of gastroesophageal reflux disease.
PG  - 43-52
LID - 10.1111/nyas.12231 [doi]
AB  - Gastroesophageal reflux disease (GERD) is highly associated with a range of 
      respiratory symptoms, arising from a variety of etiologies. The following 
      commentaries on respiratory manifestations of GERD address evidence for a role of 
      a vagally mediated bronchoconstriction reflex in the development of asthma; the 
      direct effects of airway obstruction on lower esophageal sphincter (LES) pressure 
      and reflux episodes; the mechanisms by which reflux may play roles in chronic 
      cough and airway stenosis; the limited efficacy of laparoscopic antireflux 
      surgery (LARS) in improving GERD-related respiratory symptoms; the search for a 
      marker for microaspiration and reflux-induced airway disease; and the potential 
      of proton pump inhibitor (PPI) treatment for patients presenting with asthma and 
      GERD.
CI  - (c) 2013 New York Academy of Sciences.
FAU - Harding, Susan M
AU  - Harding SM
AD  - Department of Medicine/Pulmonary Allergy & Critical Care, University of Alabama 
      at Birmingham, Birmingham, Alabama.
FAU - Allen, Jacqui E
AU  - Allen JE
AD  - Department of Otolaryngology, Northshore Hospital, Auckland, New Zealand.
FAU - Blumin, Joel H
AU  - Blumin JH
AD  - Division of Laryngology & Professional Voice, Department of Otolaryngology & 
      Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin.
FAU - Warner, Elizabeth A
AU  - Warner EA
AD  - Department of Surgery, University of Washington, Seattle, Washington.
FAU - Pellegrini, Carlos A
AU  - Pellegrini CA
AD  - Department of Surgery, University of Washington, Seattle, Washington.
FAU - Chan, Walter W
AU  - Chan WW
AD  - Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Homen's 
      Hospital, Harvard Medical School, Cambridge, Massachusetts.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Ann N Y Acad Sci
JT  - Annals of the New York Academy of Sciences
JID - 7506858
SB  - IM
MH  - Asthma/*etiology/physiopathology
MH  - Bronchoconstriction/*physiology
MH  - Cough/*etiology/physiopathology
MH  - Gastroesophageal Reflux/*complications/physiopathology
MH  - Humans
OTO - NOTNLM
OT  - GERD
OT  - asthma
OT  - bronchoconstriction
OT  - extra-esophageal reflux
EDAT- 2013/10/15 06:00
MHDA- 2013/12/19 06:00
CRDT- 2013/10/15 06:00
PHST- 2013/10/15 06:00 [entrez]
PHST- 2013/10/15 06:00 [pubmed]
PHST- 2013/12/19 06:00 [medline]
AID - 10.1111/nyas.12231 [doi]
PST - ppublish
SO  - Ann N Y Acad Sci. 2013 Oct;1300:43-52. doi: 10.1111/nyas.12231.