PMID- 24119353
OWN - NLM
STAT- MEDLINE
DCOM- 20140605
LR  - 20151119
IS  - 1878-4046 (Electronic)
IS  - 1076-6332 (Linking)
VI  - 20
IP  - 11
DP  - 2013 Nov
TI  - Dose-modified 256-MDCT of the abdomen using low tube current and hybrid iterative 
      reconstruction.
PG  - 1405-12
LID - S1076-6332(13)00350-4 [pii]
LID - 10.1016/j.acra.2013.08.004 [doi]
AB  - RATIONALE AND OBJECTIVES: To evaluate the performance of hybrid iterative 
      reconstruction technique (h-IRT) on image quality (IQ) in abdominal dose-modified 
      (DM) scans in phantom and in patients in comparison to filtered back projection 
      (FBP). MATERIALS AND METHODS: An anthropomorphic phantom was scanned using 
      various kVp (80-140) and mAs (25-100) settings. Images were reconstructed with 
      FBP and h-IRT levels (1-6). In 69 adults (59.6 +/- 13.54 years; 20 male, 
      49 female), DM computed tomography (CT) scans were performed using 120 kVp and 
      100-120 mAs. In 25/69, 5-mm FBP and h-IRT (levels 1-4 and 5) images were analyzed 
      to validate IQ. The subsequent 44/69 had FBP and h-IRT (level 4) images 
      reconstructed. Two readers evaluated 188 image series for IQ, noise, and 
      artifacts. Objective and subjective data were analyzed using t-test and Wilcoxon 
      signed-rank test, respectively. In 46/69 patients, prior dose CT was available 
      for dose comparison. RESULTS: In the phantom, noise reduction ranged from 12% 
      (h-IRT level 1) to 50% (level 6). In patients, h-IRT level 4 images were rated 
      diagnostic in 69/69 exams but DM-FBP images were found nondiagnostic in 20/69 
      patients. The size-specific dose estimate (SSDE) was reduced by 55% in the 
      dose-modified CT group, (SSDE:4.55 +/- 1.15 mGy) over the prior dose protocol 
      (SSDE:10.21 +/- 3.5 mGy, P < .0001). CONCLUSION: h-IRT improved IQ in abdominal 
      DM-CT scans in phantom and in patients. Dose improvements were greater in smaller 
      patients than larger ones.
CI  - Copyright (c) 2013 AUR. Published by Elsevier Inc. All rights reserved.
FAU - Fuentes-Orrego, Jorge M
AU  - Fuentes-Orrego JM
AD  - Division of Abdominal Imaging and Intervention, Department of Radiology, 
      Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, 
      MA 02115.
FAU - Hayano, Koichi
AU  - Hayano K
FAU - Kambadakone, Avinash R
AU  - Kambadakone AR
FAU - Hahn, Peter F
AU  - Hahn PF
FAU - Sahani, Dushyant V
AU  - Sahani DV
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Acad Radiol
JT  - Academic radiology
JID - 9440159
RN  - 0 (Contrast Media)
SB  - IM
MH  - Contrast Media
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multidetector Computed Tomography/*methods
MH  - Phantoms, Imaging
MH  - Radiation Dosage
MH  - Radiographic Image Interpretation, Computer-Assisted/*methods
MH  - Radiography, Abdominal/*methods
OTO - NOTNLM
OT  - Radiation dose
OT  - abdomen
OT  - computed tomography
OT  - image quality
OT  - iterative reconstruction
EDAT- 2013/10/15 06:00
MHDA- 2014/06/06 06:00
CRDT- 2013/10/15 06:00
PHST- 2013/07/10 00:00 [received]
PHST- 2013/08/06 00:00 [revised]
PHST- 2013/08/06 00:00 [accepted]
PHST- 2013/10/15 06:00 [entrez]
PHST- 2013/10/15 06:00 [pubmed]
PHST- 2014/06/06 06:00 [medline]
AID - S1076-6332(13)00350-4 [pii]
AID - 10.1016/j.acra.2013.08.004 [doi]
PST - ppublish
SO  - Acad Radiol. 2013 Nov;20(11):1405-12. doi: 10.1016/j.acra.2013.08.004.