PMID- 24120406 OWN - NLM STAT- MEDLINE DCOM- 20140630 LR - 20220311 IS - 1573-2517 (Electronic) IS - 0165-0327 (Linking) VI - 152-154 DP - 2014 Jan TI - Comorbidity of personality disorders in mood disorders: a meta-analytic review of 122 studies from 1988 to 2010. PG - 1-11 LID - S0165-0327(13)00657-5 [pii] LID - 10.1016/j.jad.2013.08.023 [doi] AB - BACKGROUND: A meta-analysis was conducted to identify the proportions of comorbid personality disorders (PD) in mood disorders. METHODS: We found 122 empirical papers published in the period 1980-2010 on participants having mood disorders in addition to a comorbid PD. Mood disorders were classified as bipolar disorders (BD), major depressive disorders (MDD) and dysthymic disorders (DYS). Several moderators were coded as well. RESULTS: The risk of having at least one comorbid PD (any PD) was high across all three mood disorders (BD=.42, MDD=.45), but highest in DYS (.60). Cluster B and C PDs were most frequent in BD, while cluster C PDs dominated in MDD and DYS. Among the specific PDs, the paranoid (.11 versus .07/.05), borderline (.16 versus .14/.13), histrionic (.10 versus .06/.06) and obsessive-compulsive (.18 versus .09/.12) PDs occurred more frequently in BD versus MDD/DYS, whereas the avoidant PD (.22 versus .12/.16) was most frequent in DYS versus BD/MDD. Moderator analyses showed higher comorbidity when diagnoses were based on questionnaires versus clinical interviews, DSM-III-R versus DSM-IV, more women were included or the duration of the disorder was longer. Age of onset yielded mixed results. LIMITATIONS: Blind rating of diagnoses was recorded, but was employed in too few studies to be usable as an indication of diagnostic validity. CONCLUSIONS: Personality disorders are common in mood disorders. Implications of the identified moderators as well as the new DSM-5 diagnostic system are considered. CI - (c) 2013 Elsevier B.V. All rights reserved. FAU - Friborg, Oddgeir AU - Friborg O AD - Department of Psychology, Faculty of Health Sciences, University of Tromso, N-9037 Tromso, Norway; Department of Psychiatric Research, University Hospital of North Norway, Tromso, Norway. Electronic address: oddgeir.friborg@uit.no. FAU - Martinsen, Egil W AU - Martinsen EW FAU - Martinussen, Monica AU - Martinussen M FAU - Kaiser, Sabine AU - Kaiser S FAU - Overgard, Karl Tore AU - Overgard KT FAU - Rosenvinge, Jan H AU - Rosenvinge JH LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't DEP - 20130902 PL - Netherlands TA - J Affect Disord JT - Journal of affective disorders JID - 7906073 SB - IM MH - Age of Onset MH - Aged MH - Bipolar Disorder/epidemiology MH - Borderline Personality Disorder/epidemiology MH - Comorbidity MH - Depressive Disorder, Major/epidemiology MH - Dysthymic Disorder/epidemiology MH - Female MH - Histrionic Personality Disorder/epidemiology MH - Humans MH - Male MH - Middle Aged MH - Mood Disorders/*epidemiology MH - Obsessive-Compulsive Disorder/epidemiology MH - Paranoid Personality Disorder/epidemiology MH - Personality Disorders/*epidemiology MH - Risk Factors MH - Sex Factors OTO - NOTNLM OT - Bipolar disorder OT - Comorbidity OT - Dysthymic disorders OT - Meta-analysis OT - Personality disorders OT - Unipolar depressive disorders EDAT- 2013/10/15 06:00 MHDA- 2014/07/01 06:00 CRDT- 2013/10/15 06:00 PHST- 2013/05/13 00:00 [received] PHST- 2013/08/19 00:00 [revised] PHST- 2013/08/20 00:00 [accepted] PHST- 2013/10/15 06:00 [entrez] PHST- 2013/10/15 06:00 [pubmed] PHST- 2014/07/01 06:00 [medline] AID - S0165-0327(13)00657-5 [pii] AID - 10.1016/j.jad.2013.08.023 [doi] PST - ppublish SO - J Affect Disord. 2014 Jan;152-154:1-11. doi: 10.1016/j.jad.2013.08.023. Epub 2013 Sep 2.