PMID- 24122663
OWN - NLM
STAT- MEDLINE
DCOM- 20140512
LR  - 20140326
IS  - 1758-1052 (Electronic)
IS  - 0956-4624 (Linking)
VI  - 25
IP  - 5
DP  - 2014 Apr
TI  - Early development of immune reconstitution inflammatory syndrome related to 
      Pneumocystis pneumonia after antiretroviral therapy.
PG  - 373-7
LID - 10.1177/0956462413506888 [doi]
AB  - Immune reconstitution inflammatory syndrome is a recognized complication after 
      the initiation of combination antiretroviral therapy (cART). We report a patient 
      who developed life-threatening pulmonary immune reconstitution inflammatory 
      syndrome (IRIS) three days after initiation of cART. We reviewed published cases 
      of IRIS after Pneumocystis pneumonia (PCP), in particular the time from 
      initiation of cART to IRIS event. The median duration from the initiation of cART 
      to the onset of IRIS was 15 days in the 33 patients reviewed. This report alerts 
      clinicians to the rapidity of the development of pulmonary IRIS following PCP 
      after the initiation of cART.
FAU - Mok, Hoi Ping
AU  - Mok HP
AD  - Department of Infectious Diseases, Addenbrooke's Hospital, Cambridge, UK.
FAU - Hart, Elizabeth
AU  - Hart E
FAU - Venkatesan, Pradhib
AU  - Venkatesan P
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20131011
PL  - England
TA  - Int J STD AIDS
JT  - International journal of STD & AIDS
JID - 9007917
RN  - 0 (Anti-HIV Agents)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/drug therapy/*etiology/virology
MH  - Adult
MH  - Anti-HIV Agents/*adverse effects/therapeutic use
MH  - CD4 Lymphocyte Count
MH  - HIV Infections/complications/*drug therapy/immunology
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*complications
MH  - Male
MH  - Pneumonia, Pneumocystis/*complications/drug therapy/virology
MH  - Treatment Outcome
MH  - Viral Load
OTO - NOTNLM
OT  - AIDS
OT  - HIV
OT  - IRIS
OT  - Pneumocystis jirovecii
OT  - Pneumocystis pneumonia
OT  - antiretroviral therapy
OT  - immune reconstitution inflammatory syndrome
EDAT- 2013/10/15 06:00
MHDA- 2014/05/13 06:00
CRDT- 2013/10/15 06:00
PHST- 2013/10/15 06:00 [entrez]
PHST- 2013/10/15 06:00 [pubmed]
PHST- 2014/05/13 06:00 [medline]
AID - 0956462413506888 [pii]
AID - 10.1177/0956462413506888 [doi]
PST - ppublish
SO  - Int J STD AIDS. 2014 Apr;25(5):373-7. doi: 10.1177/0956462413506888. Epub 2013 
      Oct 11.