PMID- 24126152
OWN - NLM
STAT- MEDLINE
DCOM- 20150105
LR  - 20220409
IS  - 1476-5411 (Electronic)
IS  - 1367-0484 (Linking)
VI  - 37
IP  - 3
DP  - 2014 Jun
TI  - Dry eye disease: prevalence, distribution and determinants in a hospital-based 
      population.
PG  - 157-61
LID - S1367-0484(13)00279-8 [pii]
LID - 10.1016/j.clae.2013.09.009 [doi]
AB  - OBJECTIVES: To determine the prevalence, distribution and risk factors for dry 
      eye disease (DED) in a tertiary ophthalmic outpatient population. METHODS: The 
      study was a cross-sectional descriptive hospital-based survey conducted at the 
      Eye clinic of the University of Nigeria Teaching Hospital (UNTH), Enugu, between 
      September and December, 2011. The participants comprised adult ophthalmic 
      outpatients aged 18 years or older. Participants' sociodemographic data were 
      obtained. Dry eye disease was assessed subjectively with the Ocular Surface 
      Disease Index (OSDI) questionnaire; and objectively with Schirmer's test and 
      Tear-film Break-up Time (TBUT). An OSDI score of >/= 50 with a TBUT of <10s or 
      Schirmer's test reading of <10mm was considered diagnostic of DED. Descriptive 
      and analytical statistics were performed. In all comparisons, a p<0.05 was 
      considered statistically significant. RESULTS: The participants (n=402) comprised 
      193 males and 209 females who were aged 50.1 +/- 19.06 SD years (range 18-94 
      years). The majorities of the participants were married - 74.1%, possessed formal 
      education - 86.0% and were civil servants - 33.6%. The prevalence of DED was 
      19.2%. Dry eye disease was significantly associated with age>40 years (OR 1.88, 
      95% CI 1.06-3.35, p=0.0004), non-possession of formal education (OR 0.40, 95% CI 
      0.21-0.74, p=0.001) but not gender (OR 1.48, 95% CI 0.89-2.46, p=0.158). 
      CONCLUSION: The prevalence of DED among ophthalmic outpatients at UNTH, Enugu, is 
      comparatively high. Older age and illiteracy are predictors of DED. There is need 
      for high index of diagnostic suspicion to prevent sight-threatening complications 
      of DED.
CI  - Copyright (c) 2013 British Contact Lens Association. Published by Elsevier Ltd. All 
      rights reserved.
FAU - Onwubiko, Stella N
AU  - Onwubiko SN
AD  - Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01139 
      Ituku-Ozalla, Enugu, Nigeria.
FAU - Eze, Boniface I
AU  - Eze BI
AD  - Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01139 
      Ituku-Ozalla, Enugu, Nigeria. Electronic address: xy3165767@yahoo.com.
FAU - Udeh, Nnemma N
AU  - Udeh NN
AD  - Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01139 
      Ituku-Ozalla, Enugu, Nigeria.
FAU - Arinze, Obinna C
AU  - Arinze OC
AD  - Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01139 
      Ituku-Ozalla, Enugu, Nigeria.
FAU - Onwasigwe, Ernest N
AU  - Onwasigwe EN
AD  - Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01139 
      Ituku-Ozalla, Enugu, Nigeria.
FAU - Umeh, Rich E
AU  - Umeh RE
AD  - Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01139 
      Ituku-Ozalla, Enugu, Nigeria.
LA  - eng
PT  - Journal Article
DEP - 20131011
PL  - England
TA  - Cont Lens Anterior Eye
JT  - Contact lens & anterior eye : the journal of the British Contact Lens Association
JID - 9712714
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Ambulatory Care/*statistics & numerical data
MH  - Child
MH  - Dry Eye Syndromes/*diagnosis/*epidemiology
MH  - *Educational Status
MH  - Female
MH  - Hospitalization/*statistics & numerical data
MH  - Hospitals, University/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nigeria/epidemiology
MH  - Sex Distribution
MH  - Young Adult
OTO - NOTNLM
OT  - Determinants
OT  - Dry eye
OT  - Hospital
OT  - Population
OT  - Prevalence
EDAT- 2013/10/16 06:00
MHDA- 2015/01/06 06:00
CRDT- 2013/10/16 06:00
PHST- 2013/04/08 00:00 [received]
PHST- 2013/09/08 00:00 [revised]
PHST- 2013/09/22 00:00 [accepted]
PHST- 2013/10/16 06:00 [entrez]
PHST- 2013/10/16 06:00 [pubmed]
PHST- 2015/01/06 06:00 [medline]
AID - S1367-0484(13)00279-8 [pii]
AID - 10.1016/j.clae.2013.09.009 [doi]
PST - ppublish
SO  - Cont Lens Anterior Eye. 2014 Jun;37(3):157-61. doi: 10.1016/j.clae.2013.09.009. 
      Epub 2013 Oct 11.