PMID- 24135085
OWN - NLM
STAT- MEDLINE
DCOM- 20140902
LR  - 20211021
IS  - 1745-6215 (Electronic)
IS  - 1745-6215 (Linking)
VI  - 14
DP  - 2013 Oct 17
TI  - Mothers After Gestational Diabetes in Australia Diabetes Prevention Program 
      (MAGDA-DPP) post-natal intervention: study protocol for a randomized controlled 
      trial.
PG  - 339
LID - 10.1186/1745-6215-14-339 [doi]
AB  - BACKGROUND: Gestational diabetes mellitus (GDM) is defined as glucose intolerance 
      with its onset or first recognition during pregnancy. Post-GDM women have a 
      life-time risk exceeding 70% of developing type 2 diabetes mellitus (T2DM). 
      Lifestyle modifications reduce the incidence of T2DM by up to 58% for high-risk 
      individuals. METHODS/DESIGN: The Mothers After Gestational Diabetes in Australia 
      Diabetes Prevention Program (MAGDA-DPP) is a randomized controlled trial aiming 
      to assess the effectiveness of a structured diabetes prevention intervention for 
      post-GDM women. This trial has an intervention group participating in a diabetes 
      prevention program (DPP), and a control group receiving usual care from their 
      general practitioners during the same time period. The 12-month intervention 
      comprises an individual session followed by five group sessions at two-week 
      intervals, and two follow-up telephone calls. A total of 574 women will be 
      recruited, with 287 in each arm. The women will undergo blood tests, 
      anthropometric measurements, and self-reported health status, diet, physical 
      activity, quality of life, depression, risk perception and healthcare service 
      usage, at baseline and 12 months. At completion, primary outcome (changes in 
      diabetes risk) and secondary outcome (changes in psychosocial and quality of life 
      measurements and in cardiovascular disease risk factors) will be assessed in both 
      groups. DISCUSSION: This study aims to show whether MAGDA-DPP leads to a 
      reduction in diabetes risk for post-GDM women. The characteristics that predict 
      intervention completion and improvement in clinical and behavioral measures will 
      be useful for further development of DPPs for this population. TRIAL 
      REGISTRATION: Australian New Zealand Clinical Trials Registry ANZCTRN 
      12610000338066.
FAU - Shih, Sophy T F
AU  - Shih ST
FAU - Davis-Lameloise, Nathalie
AU  - Davis-Lameloise N
FAU - Janus, Edward D
AU  - Janus ED
FAU - Wildey, Carol
AU  - Wildey C
FAU - Versace, Vincent L
AU  - Versace VL
FAU - Hagger, Virginia
AU  - Hagger V
FAU - Asproloupos, Dino
AU  - Asproloupos D
FAU - O'Reilly, Sharleen
AU  - O'Reilly S
FAU - Phillips, Paddy A
AU  - Phillips PA
FAU - Ackland, Michael
AU  - Ackland M
FAU - Skinner, Timothy
AU  - Skinner T
FAU - Oats, Jeremy
AU  - Oats J
FAU - Carter, Rob
AU  - Carter R
FAU - Best, James D
AU  - Best JD
FAU - Dunbar, James A
AU  - Dunbar JA
AD  - Greater Green Triangle University Department of Rural Health, Flinders 
      University, PO Box 423, Warrnambool VIC 3280, Australia. 
      director@greaterhealth.org.
CN  - MAGDA Research Group
LA  - eng
SI  - ANZCTR/ANZCTRN1261000033806
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20131017
PL  - England
TA  - Trials
JT  - Trials
JID - 101263253
SB  - IM
MH  - Australia
MH  - Clinical Protocols
MH  - Diabetes Mellitus, Type 2/diagnosis/etiology/*prevention & control
MH  - Diabetes, Gestational/diagnosis/*therapy
MH  - Female
MH  - Humans
MH  - Postnatal Care/*methods
MH  - Pregnancy
MH  - Prospective Studies
MH  - *Research Design
MH  - Risk Factors
MH  - *Risk Reduction Behavior
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC3853589
EDAT- 2013/10/19 06:00
MHDA- 2014/09/03 06:00
PMCR- 2013/10/17
CRDT- 2013/10/19 06:00
PHST- 2013/07/29 00:00 [received]
PHST- 2013/09/26 00:00 [accepted]
PHST- 2013/10/19 06:00 [entrez]
PHST- 2013/10/19 06:00 [pubmed]
PHST- 2014/09/03 06:00 [medline]
PHST- 2013/10/17 00:00 [pmc-release]
AID - 1745-6215-14-339 [pii]
AID - 10.1186/1745-6215-14-339 [doi]
PST - epublish
SO  - Trials. 2013 Oct 17;14:339. doi: 10.1186/1745-6215-14-339.