PMID- 2414060 OWN - NLM STAT- MEDLINE DCOM- 19851125 LR - 20071115 IS - 0010-8650 (Print) IS - 0010-8650 (Linking) VI - 27 IP - 4 DP - 1985 TI - Spontaneous variability and detection of repetitive extrasystoles during simulated acute antiarrhythmic testing. PG - 287-92 AB - In order to estimate the reduction in ventricular premature contractions (VPCs) due to spontaneous variability during simulated acute antiarrhythmic testing, and also to determine the detection capacity for repetitive VPCs during short periods of ECG monitoring usually employed as baseline recordings, 2 groups of patients were studied A reduction by more than 50% of the baseline VPC-rate can be expected to occur as a result of an antiarrhythmic intervention, while approximately 40% of the patients with repetitive high risk VPCs escape detection during short periods of control recordings. It is suggested to use a 24 to 47-hour ambulatory monitoring for the diagnosis and classification of VPCs, while acute antiarrhythmic testing should be employed for assessing individual efficacy and tolerance. FAU - Hernandez-Acosta, K AU - Hernandez-Acosta K FAU - Groning, E AU - Groning E FAU - Rodriguez-Bereao, C AU - Rodriguez-Bereao C FAU - Hernandez-Canero, A AU - Hernandez-Canero A FAU - Garcia-Barreto, D AU - Garcia-Barreto D LA - eng PT - Journal Article PL - Czech Republic TA - Cor Vasa JT - Cor et vasa JID - 0372614 RN - 0 (Anti-Arrhythmia Agents) SB - IM MH - Anti-Arrhythmia Agents/*therapeutic use MH - Arrhythmias, Cardiac/diagnosis/drug therapy MH - Cardiac Complexes, Premature/*diagnosis/physiopathology MH - Drug Evaluation MH - Electrocardiography MH - Humans MH - Monitoring, Physiologic MH - Regression Analysis EDAT- 1985/01/01 00:00 MHDA- 1985/01/01 00:01 CRDT- 1985/01/01 00:00 PHST- 1985/01/01 00:00 [pubmed] PHST- 1985/01/01 00:01 [medline] PHST- 1985/01/01 00:00 [entrez] PST - ppublish SO - Cor Vasa. 1985;27(4):287-92.