PMID- 24143037 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211021 IS - 0167-9473 (Print) IS - 0167-9473 (Linking) VI - 55 IP - 1 DP - 2011 Jan 1 TI - Understanding and comparisons of different sampling approaches for the Fourier Amplitudes Sensitivity Test (FAST). PG - 184-198 AB - Fourier Amplitude Sensitivity Test (FAST) is one of the most popular uncertainty and sensitivity analysis techniques. It uses a periodic sampling approach and a Fourier transformation to decompose the variance of a model output into partial variances contributed by different model parameters. Until now, the FAST analysis is mainly confined to the estimation of partial variances contributed by the main effects of model parameters, but does not allow for those contributed by specific interactions among parameters. In this paper, we theoretically show that FAST analysis can be used to estimate partial variances contributed by both main effects and interaction effects of model parameters using different sampling approaches (i.e., traditional search-curve based sampling, simple random sampling and random balance design sampling). We also analytically calculate the potential errors and biases in the estimation of partial variances. Hypothesis tests are constructed to reduce the effect of sampling errors on the estimation of partial variances. Our results show that compared to simple random sampling and random balance design sampling, sensitivity indices (ratios of partial variances to variance of a specific model output) estimated by search-curve based sampling generally have higher precision but larger underestimations. Compared to simple random sampling, random balance design sampling generally provides higher estimation precision for partial variances contributed by the main effects of parameters. The theoretical derivation of partial variances contributed by higher-order interactions and the calculation of their corresponding estimation errors in different sampling schemes can help us better understand the FAST method and provide a fundamental basis for FAST applications and further improvements. FAU - Xu, Chonggang AU - Xu C AD - Department of Entomology and Center for Quantitative Sciences in Biomedicine, North Carolina State University, Raleigh, NC 27695, USA. FAU - Gertner, George AU - Gertner G LA - eng GR - R01 AI054954/AI/NIAID NIH HHS/United States PT - Journal Article PL - Netherlands TA - Comput Stat Data Anal JT - Computational statistics & data analysis JID - 100960938 PMC - PMC3798038 MID - NIHMS482129 OTO - NOTNLM OT - Fourier Amplitude Sensitivity Test OT - Interactions OT - Random balance design OT - Sensitivity analysis OT - Simple random sampling OT - Uncertainty analysis EDAT- 2011/01/01 00:00 MHDA- 2011/01/01 00:01 PMCR- 2013/10/17 CRDT- 2013/10/22 06:00 PHST- 2013/10/22 06:00 [entrez] PHST- 2011/01/01 00:00 [pubmed] PHST- 2011/01/01 00:01 [medline] PHST- 2013/10/17 00:00 [pmc-release] AID - 10.1016/j.csda.2010.06.028 [doi] PST - ppublish SO - Comput Stat Data Anal. 2011 Jan 1;55(1):184-198. doi: 10.1016/j.csda.2010.06.028.