PMID- 24148515
OWN - NLM
STAT- MEDLINE
DCOM- 20140603
LR  - 20161125
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 116
DP  - 2013 Nov 15
TI  - One-step fabrication of bio-functionalized nanoporous 
      gold/poly(3,4-ethylenedioxythiophene) hybrid electrodes for amperometric glucose 
      sensing.
PG  - 1054-9
LID - S0039-9140(13)00672-3 [pii]
LID - 10.1016/j.talanta.2013.08.014 [doi]
AB  - We report a simple, one-step synthesis of hybrid film by electropolymerizing 
      3,4-ethylenedioxythiophene (EDOT) on nanoporous gold (NPG) for applications in 
      amperometric glucose biosensors. The enzyme, glucose oxidase (GOx), is entrapped 
      into poly(3,4-ethylenedioxythiophene) (PEDOT) matrix, simultaneously. Scanning 
      electron microscope (SEM) and transmission electron microscopy (TEM) studies show 
      the NPG preserve its original bicontinuous nanoporous structure and the PEDOT 
      film grows uniformly with a thickness of ~10 nm. The modified electrodes have 
      been investigated by cyclic voltammetry (CV) and single potential step 
      chronoamperometry (SPSC). The influence of PEDOT film's thickness has been 
      explored to optimize sensor behaviors. Mediated by p-benzoquinone (BQ), the 
      calibration curves have been obtained by applying relatively low constant 
      potential of 200 mV (vs. SCE). The NPG/PEDOT/GOx (2CVs) biosensor exhibits high 
      sensitivity of 7.3 muA mM(-1) cm(-2) and a wide linear range of 0.1-15 mM, making 
      it suitable for reliable analytic applications.
CI  - (c) 2013 Elsevier B.V. All rights reserved.
FAU - Xiao, Xinxin
AU  - Xiao X
AD  - Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, 
      Ministry of Education, School of Materials Science and Engineering, Shandong 
      University, Jinan 250061, People's Republic of China.
FAU - Wang, Meng'en
AU  - Wang M
FAU - Li, Hui
AU  - Li H
FAU - Si, Pengchao
AU  - Si P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130817
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Benzoquinones)
RN  - 0 (Bridged Bicyclo Compounds, Heterocyclic)
RN  - 0 (Enzymes, Immobilized)
RN  - 0 (Polymers)
RN  - 0 (Solutions)
RN  - 0 (poly(3,4-ethylene dioxythiophene))
RN  - 3T006GV98U (quinone)
RN  - 7440-57-5 (Gold)
RN  - EC 1.1.3.4 (Glucose Oxidase)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Benzoquinones/chemistry
MH  - *Biosensing Techniques
MH  - Bridged Bicyclo Compounds, Heterocyclic/*chemistry
MH  - Calibration
MH  - Electrochemical Techniques
MH  - Electrodes
MH  - Enzymes, Immobilized/chemistry
MH  - Glucose/*analysis
MH  - Glucose Oxidase/chemistry
MH  - Gold/*chemistry
MH  - Polymers/*chemistry
MH  - Porosity
MH  - Sensitivity and Specificity
MH  - Solutions
OTO - NOTNLM
OT  - Electropolymerization
OT  - Glucose biosensor
OT  - Nanoporous gold
OT  - Poly(3,4-ethylenedioxythiophene)
EDAT- 2013/10/24 06:00
MHDA- 2014/06/04 06:00
CRDT- 2013/10/24 06:00
PHST- 2013/05/15 00:00 [received]
PHST- 2013/07/31 00:00 [revised]
PHST- 2013/08/11 00:00 [accepted]
PHST- 2013/10/24 06:00 [entrez]
PHST- 2013/10/24 06:00 [pubmed]
PHST- 2014/06/04 06:00 [medline]
AID - S0039-9140(13)00672-3 [pii]
AID - 10.1016/j.talanta.2013.08.014 [doi]
PST - ppublish
SO  - Talanta. 2013 Nov 15;116:1054-9. doi: 10.1016/j.talanta.2013.08.014. Epub 2013 
      Aug 17.