PMID- 24151569
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20131023
LR  - 20211021
IS  - 2090-6668 (Print)
IS  - 2090-6676 (Electronic)
IS  - 2090-6676 (Linking)
VI  - 2013
DP  - 2013
TI  - A Rare Case of Immune Reconstitution Inflammatory Syndrome Development in an 
      Immunocompromised Patient with Progressive Multifocal Leukoencephalopathy and 
      Multicentric Castleman's Disease.
PG  - 460701
LID - 10.1155/2013/460701 [doi]
LID - 460701
AB  - Immune reconstitution inflammatory syndrome (IRIS) development in HIV with 
      preexistent progressive multifocal leukoencephalopathy (PML) has been extensively 
      studied. PML-IRIS typically manifests clinically as new or worsening neurologic 
      symptoms in conjunction with enlarging CNS lesions and occurs in approximately 
      10-20 percent of HIV-infected patients with PML who begin HAART. Likewise, 
      Multicentric Castleman's Disease (MCD), a rare malignant lymphoproliferative 
      disorder, has a strong and well-known association with HIV. Our case provides a 
      rare instance of PML-IRIS in combination with MCD in an HIV-positive individual. 
      The combination of all three diseases has never been reported in the literature. 
      Both MCD and PML were present during initial determination of HIV infection in 
      our patient and their disease courses were altered during the subsequent 
      development of IRIS.
FAU - Kurukumbi, Mohankumar
AU  - Kurukumbi M
AD  - Department of Neurology, Howard University Hospital, 2041 Georgia Avenue, 
      Washington, DC 20060, USA.
FAU - Steiner, Sheldon
AU  - Steiner S
FAU - Dunlap, Shariff
AU  - Dunlap S
FAU - Chapman, Sherita
AU  - Chapman S
FAU - Solieman, Noha
AU  - Solieman N
FAU - Jayam-Trouth, Annapurni
AU  - Jayam-Trouth A
LA  - eng
PT  - Journal Article
DEP - 20130819
PL  - United States
TA  - Case Rep Neurol Med
JT  - Case reports in neurological medicine
JID - 101576451
PMC - PMC3760301
EDAT- 2013/10/24 06:00
MHDA- 2013/10/24 06:01
PMCR- 2013/08/19
CRDT- 2013/10/24 06:00
PHST- 2013/06/27 00:00 [received]
PHST- 2013/07/17 00:00 [accepted]
PHST- 2013/10/24 06:00 [entrez]
PHST- 2013/10/24 06:00 [pubmed]
PHST- 2013/10/24 06:01 [medline]
PHST- 2013/08/19 00:00 [pmc-release]
AID - 10.1155/2013/460701 [doi]
PST - ppublish
SO  - Case Rep Neurol Med. 2013;2013:460701. doi: 10.1155/2013/460701. Epub 2013 Aug 
      19.