PMID- 24160953
OWN - NLM
STAT- MEDLINE
DCOM- 20141008
LR  - 20131028
IS  - 0210-5705 (Print)
IS  - 0210-5705 (Linking)
VI  - 36 Suppl 2
DP  - 2013 Oct
TI  - [Update on non-variceal gastrointestinal bleeding].
PG  - 57-65
LID - S0210-5705(13)70054-2 [pii]
LID - 10.1016/S0210-5705(13)70054-2 [doi]
AB  - This article summarizes the main studies in the field of non-variceal 
      gastrointestinal bleeding reported in the last American Congress of 
      Gastroenterology (Digestive Disease Week) in 2013. Some of these studies have 
      provided new knowledge and expertise in areas of uncertainty. In this context and 
      among other findings, it has been reported that the administration of a proton 
      pump inhibitor (PPI) prior to endoscopy or the early performance of 
      endoscopy-within 6 hours of admission in patients with upper gastrointestinal 
      bleeding (UGIB) (or colonoscopy within 24 hours in patients with lower 
      gastrointestinal bleeding)-does not improve the prognosis of the event. It has 
      also been reported that oral administration of a PPI after endoscopic hemostasis 
      may produce a similar outcome to that of intravenously administered PPI in 
      patients with upper gastrointestinal bleeding (UGIB). In the field of endoscopic 
      therapy, the use of radiofrequency ablation for antral vascular ectasia is of 
      interest. Regarding UGIB and nonsteroidal antiinflammatory drugs (NSAIDs), new 
      data confirm the risk of cardiovascular events by stopping treatment with 
      acetylsalicylic acid (ASA) after an episode of UGIB, the increased risk of UGIB 
      when associating gastrotoxic drugs, and the need to identify both the 
      gastrointestinal and cardiovascular risks of each NSAID and coxib when 
      prescribing these agents. Finally, there is evidence that both environmental and 
      genetic factors are involved in individual susceptibility to gastrointestinal 
      bleeding.
CI  - Copyright (c) 2013 Elsevier Espana, S.L. All rights reserved.
FAU - Lanas, Angel
AU  - Lanas A
AD  - Servicio de Aparato Digestivo, Hospital Clinico Universitario Lozano Blesa, 
      Universidad de Zaragoza, IIS Aragon, CIBERehd, Zaragoza, Espana. Electronic 
      address: alanas@unizar.es.
LA  - spa
PT  - English Abstract
PT  - Journal Article
TT  - Actualizacion en hemorragia gastrointestinal de origen no varicoso.
PL  - Spain
TA  - Gastroenterol Hepatol
JT  - Gastroenterologia y hepatologia
JID - 8406671
RN  - 0 (Anti-Inflammatory Agents, Non-Steroidal)
SB  - IM
MH  - Anti-Inflammatory Agents, Non-Steroidal/adverse effects
MH  - Endoscopy, Gastrointestinal
MH  - *Gastrointestinal Hemorrhage/diagnosis/etiology/therapy
MH  - Humans
OTO - NOTNLM
OT  - Antiinflamatorios no esteroideos
OT  - Colonic diverticuli
OT  - Diverticulosis
OT  - Endoscopia
OT  - Gastrointestinal bleeding
OT  - Hemorragia gastrointestinal
OT  - Inhibidor de la bomba de protones
OT  - Nonsteroidal antiinflammatory
OT  - Peptic ulcer
OT  - Proton pump inhibitors
OT  - Acido acetilsalicilico
OT  - Ulcera peptica
EDAT- 2013/11/06 06:00
MHDA- 2014/10/09 06:00
CRDT- 2013/10/29 06:00
PHST- 2013/10/29 06:00 [entrez]
PHST- 2013/11/06 06:00 [pubmed]
PHST- 2014/10/09 06:00 [medline]
AID - S0210-5705(13)70054-2 [pii]
AID - 10.1016/S0210-5705(13)70054-2 [doi]
PST - ppublish
SO  - Gastroenterol Hepatol. 2013 Oct;36 Suppl 2:57-65. doi: 
      10.1016/S0210-5705(13)70054-2.